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Home - News - Do you know China Largest Manufacturer factory supply 1,3-Dihydroxyacetone(DHA) CAS 96-26-4 ?

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Do you know China Largest Manufacturer factory supply 1,3-Dihydroxyacetone(DHA) CAS 96-26-4 ?

June 20, 2023

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1,3-Dihydroxyacetone Basic information
Product Name: 1,3-Dihydroxyacetone
Synonyms: PROPANE-1,3-DIOL-2-ONE;1,3-dihydroxy-2-propanon;1,3-Dihydroxydimethyl ketone;1,3-Dihydroxypropanone;Aliphatic ketone;Chromelin;Dihyxal;Ketochromin
CAS: 96-26-4
MF: C3H6O3
MW: 90.08
EINECS: 202-494-5
Product Categories: Pharmaceutical intermediates;Imidazoles;96-26-4;bc0001
Mol File: 96-26-4.mol
1,3-Dihydroxyacetone Structure
1,3-Dihydroxyacetone Chemical Properties
Melting point 75-80 °C
Boiling point 107.25°C (rough estimate)
density 1.1385 (rough estimate)
vapor pressure 0.002-0.33Pa at 20-50℃
refractive index 1.4540 (estimate)
storage temp. Store at +2°C to +8°C.
solubility >112.4 mg/mL in DMSO; >5.09 mg/mL in EtOH with ultrasonic
form powder
pka 12.45±0.10(Predicted)
color White
Odor at 100.00 %. minty
Odor Type minty
Water Solubility >250 g/L (20 ºC)
JECFA Number 1716
Stability: Stable. Combustible. Hygroscopic.
LogP -1.95 at 20℃
Surface tension 68.85mN/m at 1g/L and 20℃
CAS DataBase Reference 96-26-4(CAS DataBase Reference)
NIST Chemistry Reference 2-Propanone, 1,3-dihydroxy-(96-26-4)
EPA Substance Registry System 2-Propanone, 1,3-dihydroxy- (96-26-4)
Safety Information
Safety Statements 24/25
HS Code 29141900
Hazardous Substances Data 96-26-4(Hazardous Substances Data)
MSDS Information
1,3-Dihydroxyacetone Usage And Synthesis
Chemical Properties white powder
Chemical Properties Dihydroxyacetone has a characteristic sweet, cooling aroma.
Occurrence A derivative of naturally occurring starch
Uses 1,3-Dihydroxyacetone can be used as artificial tanning agent.
Uses 1,3-Dihydroxyacetone (DHA) is a self-tanning agent used in cosmetics designed to provide a tanned appearance without the need for sun exposure. It is also a uV protector and a color additive. As a self-tanning agent, it reacts with amino acids found on the skin’s epidermal layer. Its effects last only a few days as the color it provides fades with the natural shedding of the stained cells. Reportedly, it works best on slightly acidic skin. DHA, when combined with lawsone, becomes an FDA Category I (approved) uV protectant. In 1973, the FDA declared that DHA is safe and suitable for use in cosmetics or drugs that are applied to color the skin, and has exempted it from color additive certification.
Uses These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Preparation 1,3-dihydroxyacetone (DHA) is prepared by acetalization, oxidation, and hydrolysis of glycerol. Usually produced commercially from Bacillus macerans or Bacillus circulans fermentation of starch or starch hydrolysate
Definition ChEBI: Dihydroxyacetone is a ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones. It has a role as a metabolite, an antifungal agent, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a ketotriose and a primary alpha-hydroxy ketone.
Taste threshold values Reported to have a taste threshold value lower than that of sucrose with a detection level of 3.9 to 27 ppm and a recognition level of 11 to 52 ppm.
General Description Dihydroxyacetone (DHA) is a browning ingredient widely used in cosmetics such as sunless tanning formulations. It participates in a chemical staining reaction called Milliard reaction in which it reacts with the amino groups of proteins to result in a mixture of high molecular weight pigments.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Safety Profile Mutation data reported. When heated to decompositionit emits acrid smoke and irritating vapors.