China Largest Factory Manufacturer Supply Fursultiamine CAS 804-30-8 For Stock Delivery
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Purity99.9%
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UseHealth Care
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OriginChina
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Package1KG/Tin 25KG/Drum*Carton
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ManufacturerXI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
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Place of OriginCHINA
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Brand NameLeader
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CertificationISO,GMP,SGS,HALA,KOSER,HACCP
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Model NumberLD
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Minimum Order Quantity25KGS
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PriceNegotiate Depend on order quantity
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Packaging Details25KG/Drum
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Delivery Time2-3 working days
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Payment TermsWestern Union, MoneyGram, T/T, L/C
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Supply Ability10MTS/Month
China Largest Factory Manufacturer Supply Fursultiamine CAS 804-30-8 For Stock Delivery
China Largest Factory Manufacturer Supply Fursultiamine CAS 804-30-8 For Stock Delivery
LEADER BIOCHEMICAL GROUP
XI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
Tel: + 0086-02968895030/ 02968569961 Fax: +0086-02968569962
MB : +0086-13772156591 Skype: leaderbiogroup Email: info@leader-biogroup.com
| Fursultiamine Basic information |
| Product Name: | Fursultiamine |
| Synonyms: | ;Fursutiamine;Formamide, |
| CAS: | 804-30-8 |
| MF: | C17H26N4O3S2 |
| MW: | 398.54 |
| EINECS: | 212-357-1 |
| Product Categories: | Vitamins and derivatives |
| Mol File: | 804-30-8.mol |
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| Fursultiamine Chemical Properties |
| Melting point | 130-136°C (decompos.) |
| Boiling point | 652.3±55.0 °C(Predicted) |
| density | 1.29 |
| refractive index | 1.6270 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF). |
| form | Solid |
| pka | 14.42±0.10(Predicted) |
| color | White to Off-White |
| CAS DataBase Reference | 804-30-8(CAS DataBase Reference) |
| Safety Information |
| Toxicity | LD50 in rats (mg/kg): 2200 orally; 540 i.p. (Yurugi, Fushimi) |
| Fursultiamine Usage And Synthesis |
| Description | Fursultiamine (syn. thiamine tetrahydrofurfuryl disulfide) is a vitamin B1 derivative which is rarely used, is only sparingly soluble in water and thus is usually employed only for solid drug forms. Lyophilisates are stabilized by sodium dextran sulfate. |
| Chemical Properties | white or slightly yellow crystalline powder. melting point 130-136 °C (decomposition). |
| Originator | Alinamin F,Takeda,Japan,1961 |
| Uses | Fursultiamine is an oral source of thiamine, used in comparative pharmacokinectic analysis of thiamine and it’s phosphorylated metabolites administered as multivitamin preparations, identification of drug candidate against prostate cancer from aspect of somatic cell reprogramming, therapeutic tool in number of human neurological diseases. |
| Application | Fursultiamine, a lipophilic vitamin B1 derivative, which is more readily absorbed in large amounts in the small intestine and has a longer half-life than its active counterpart vitamin B1. It is suitable for the treatment of beriberi or Wernicke encephalopathy due to vitamin B1 deficiency. It can also be used for the adjuvant treatment of peripheral neuritis and indigestion caused by vitamin B1 deficiency. |
| Preparation | Furanthiamine is obtained by condensing thiamine hydrochloride with sodium tetrahydrofuranmethyl thiosulfate after ring opening. |
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