China biggest Manufacturer Factory Supply D-Isoascorbic Acid CAS 89-65-6

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Product Name:	D-Isoascorbic Acid
Synonyms:	2,3-didehydro-d-erythro-hexono-1,4-lactone;FEMA 2410;ISOASCORBIC ACID;ISOVITAMIN C;3-keto-d-erythro-hexonicacigamma-lactone;araboascorbicacid;d-arabino-ascorbicacid;d-erythro-3-ketohexonicacidlactone
CAS:	89-65-6
MF:	C6H8O6
MW:	176.12
EINECS:	201-928-0
Product Categories:	Food additive;Water Ttreatment Chemicals;Sugar Acids;Vitamin Derivatives;Biochemistry;Sugars;Food and Feed Additive;Vitamins
Mol File:	89-65-6.mol

Erythorbic Acid Chemical Properties

Melting point	169-172 °C (dec.) (lit.)
alpha	-17.25 º (c=10, H2O 25 ºC)
Boiling point	227.71°C (rough estimate)
density	1.3744 (rough estimate)
FEMA	2410 | ERYTHROBIC ACID
refractive index	-17.5 ° (C=10, H2O)
storage temp.	Store at 0-5°C
solubility	H2O: 0.1 g/mL, clear, colorless to very faintly yellow
form	Crystals or Crystalline Powder
pka	4.09±0.10(Predicted)
color	White to slightly yellow
optical activity	[α]25/D 16.8°, c = 2 in H2O
Water Solubility	1g/10mL
Merck	14,5126
BRN	84271
Stability:	Stable. Combustible. Incompatible with chemically active metals, aluminium, zinc, copper, magnesium, strong bases, strong oxidizing agents.
InChIKey	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
CAS DataBase Reference	89-65-6(CAS DataBase Reference)
EPA Substance Registry System	Isoascorbic acid (89-65-6)

Erythorbic Acid Usage And Synthesis

Chemical Properties	Erythorbic acid occurs as a white or slightly yellow-colored crystals or powder. It gradually darkens in color upon exposure to light.
Uses	Antioxidant (industrial and food), especially in brewing industry, reducing agent in photography.
Uses	Erythorbic Acid is a food preservative that is a strong reducing agent (oxygen accepting) which functions similarly to antioxidants. In the dry crystalline state it is nonreactive, but in water solutions it reacts readily with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant. During preparation, dissolving and mixing should incorporate a minimum amount of air, and storage should be at cool temperatures. It has a solubility of 43 g/100 ml of water at 25°c. One part is equivalent to one part ascorbic acid and equivalent to one part sodium erythorbate. It is used to control oxidative color and flavor deterioration in fruits at 150–200 ppm. It is used in meat curing to speed and control the nitrite curing reaction and prolong the color of cured meat at levels of 0.05%.
Production Methods	Erythorbic acid is synthesized by the reaction between methyl 2- keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose, and produced from Penicillium spp.
Biotechnological Production	Yeasts and other fungi synthesize the C5 sugar acid D-erythroascorbic acid which shares structural and physicochemical properties with Asc. D-erythroascorbic acid serves similar protective functions in these microorganisms as Asc does in plants and animals, including the scavenging of reactive oxygen species. The biosynthesis of D-erythroascorbic acid starts from D-arabinose obtained by the microorganism from decaying plant material. D-arabinose, presumably in its 1,4-furanosidic isomeric form, is oxidized by NAD(P)+ specific dehydrogenases to D-arabinono-1,4-lactone, which is further oxidized to D-erythroascorbic acid by D-arabinono-1,4-lactone oxidase. Resting cells of Saccharomyces cerevisiae can synthesize Asc from L-galactose, L-galactono-1,4-lactone, or L-gulono- 1,4-lactone via the pathway naturally used for D-erythroascorbic acid.
Pharmaceutical Applications	Erythorbic acid is a stereoisomer of L-ascorbic acid, and is used as an antioxidant in foods and oral pharmaceutical formulations. It has approximately 5% of the vitamin C activity of L-ascorbic acid.
Safety	Erythorbic acid is widely used in food applications as an antioxidant. It is also used in oral pharmaceutical applications as an antioxidant. Erythorbic acid is generally regarded as nontoxic and nonirritant when used as an excipient. Erythorbic acid is readily metabolized and does not affect the urinary excretion of ascorbic acid. The WHO has set an acceptable daily intake of erythorbic acid and its sodium salt in foods at up to 5 mg/kg body-weight.
storage	Erythorbic acid should be stored in an airtight container, protected from light, in a cool, dry place.
Purification Methods	Crystallise D(-)-isoascorbic acid from H2O, EtOH or dioxane. is at 245nm with 7,500 (EtOH). [Reichstein et al. Helv max Chim Acta 17 510, 516 1934, Heslop et al. J Chem Soc 225 1944, Beilstein 18 III/IV 3037, 18/5 V 26.]
Incompatibilities	Erythorbic acid is incompatible with chemically active metals such as aluminum, copper, magnesium, and zinc. It is also incompatible with strong bases and strong oxidizing agents.
Regulatory Status	GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral concentrate and tablets).