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China Largest Factory Manufacturer Arachidonic acid CAS 1191-85-1 For stock delivery

China Largest Factory Manufacturer Arachidonic acid CAS 1191-85-1 For stock delivery

  • Purity
    99.9%
  • Use
    Health Care
  • Origin
    China
  • Package
    1KG/Tin 25KG/Drum*Carton
  • Manufacturer
    XI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
  • Place of Origin
    CHINA
  • Brand Name
    Leader
  • Certification
    ISO,GMP,SGS,HALA,KOSER,HACCP
  • Model Number
    LD
  • Minimum Order Quantity
    25KGS
  • Price
    Negotiate Depend on order quantity
  • Packaging Details
    25KG/Drum
  • Delivery Time
    2-3 working days
  • Payment Terms
    Western Union, MoneyGram, T/T, L/C
  • Supply Ability
    10MTS/Month

China Largest Factory Manufacturer Arachidonic acid CAS 1191-85-1 For stock delivery

 
Arachidonic acid Chemical Properties
Melting point −49 °C(lit.)
Boiling point 169-171 °C0.15 mm Hg(lit.)
density 0.922 g/mL at 25 °C(lit.)
refractive index n20/D 1.4872(lit.)
Fp >230 °F
storage temp. −20°C
solubility ethanol: ≥10 mg/mL
pka 4.75±0.10(Predicted)
form oil
color colorless to light yellow
Water Solubility PRACTICALLY INSOLUBLE
Merck 14,765
BRN 1713889
InChIKey YZXBAPSDXZZRGB-DOFZRALJSA-N
CAS DataBase Reference 506-32-1(CAS DataBase Reference)
NIST Chemistry Reference Arachidonic acid(506-32-1)
 
Safety Information
Risk Statements 19
Safety Statements 24/25-19
RIDADR UN1170 - class 3 - PG 2 - Ethanol
WGK Germany 3
RTECS CE6675000
F 8-10-23
HS Code 29161900
Toxicity dns-mus:mmr 10 mg/L CRNGDP 5,1123,84
MSDS Information
Provider Language
Icosa-5,8,11,14-tetraenoic acid English
SigmaAldrich English
ACROS English
 
Arachidonic acid Usage And Synthesis
Description Arachidonic acid belongs to a kind of polyunsaturated omega-6 fatty acid, which is highly biologically relevant. It is abundantly distributed in brain, muscles and liver. It is the precursor for all prostaglandins, thromboxanes, and leukotrienes. Most cellular arachidonic acid is esterified in the membrane phospholipids. It is an important second messenger of cellular signalling participating in the regulation of signaling enzymes including PLC-γ, PLC-δ, and PKC-α, -β, and -γ isoforms. In addition, arachidonic acid acts as key inflammatory intermediate as well as avasodilator. Generally, the body can synthesize the arachidonic acid through linoleic acid. However, upon linoleic acid deficiency, it is necessary to supplement arachidonic acid from the diets. Food sources of arachidonic acid include meat, eggs and some fishes. Alternatively, we can also have arachidonic acid supplements.
References http://www.fitday.com/fitness-articles/nutrition/healthy-eating/what-is-arachidonic-acid.html
https://en.wikipedia.org/wiki/Arachidonic_acid
https://www.caymanchem.com/product/90010
Description Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6). It is the counterpart to the saturated arachidic acid found in peanut oil, (L. arachis – peanut.).
Chemical Properties In chemical structure, arachidonic acid is a carboxylic acid with a 20-carbon chain and four cis-double bonds; the first double bond is located at the sixth carbon from the omega end.
Some chemistry sources define 'arachidonic acid' to designate any of the eicosatetraenoic acids. However, almost all writings in biology, medicine and nutrition limit the term to all-cis-5,8,11,14- eicosatetraenoic acid.
Chemical Properties liquid
Uses An unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes
Uses Arachidonic Acid is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.
Uses arachidonic acid is an ingredient with skin-smoothing, emollient, and healing properties. Arachidonic acid is an omega-6 essential fatty acid naturally occurring in the skin and considered critical for appropriate skin metabolism. It is a constituent of vitamin F.
Definition ChEBI: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
Biological Activity Endogenous free fatty acid released from phospholipids by phospholipase A 2 . Important cellular signaling mediator and precursor of eicosanoids. Metabolized by lipoxygenases, cyclooxygenases and cytochrome P450 monooxygenases.
Safety Profile Poison by intravenous route.Experimental reproductive effects. Mutation datareported. When heated to decomposition it emits acridsmoke and irritating fumes.
Carcinogenicity In vitro and in vivo studies indicate that inhibition of arachidonic acid metabolism inhibits the growth of malignant cells, including head and neck squamous cell carcinoma, and implicates arachadonic acid in facilitating the metastasis of these tumor cells. Arachidonic acid reaction with cyclooxygenase and lipoxygenases yield eicosanoids that can mediate prostate cancer proliferation and enhance both tumor vascularization and metastasis. Cytochrome P450 arachidonic acid epoxygenases promote cell proliferation and inhibit apoptosis in endothelial cells.
 
Arachidonic acid Preparation Products And Raw materials
Raw materials Ethanol-->Hydrochloric acid-->Potassium hydroxide-->ZINC-->Bromide-->METHYL ARACHIDONATE
Preparation Products Prostaglandin E1 Impurity 2-->Prostaglandin E2-->EPA