| Product Name: |
D-alpha-Tocopheryl acetate |
| Synonyms: |
D-alpha-Tocopheryl acetate,98%;D-alpha-Tocopheryl acetateVitamine E-acetate;(2R)-3,4-Dihydro-2,5,7,8-tetraMethyl-2-[(4R,8R)-4,8,12-triMethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate;(2R,4'R,8'R)-α-Tocopherol Acetate;(2R,4'R,8'R)-α-Tocopheryl Acetate;(R,R,R)-α-Tocopheryl Acetate;2,5,7,8-TetraMethyl-2-(4,8,12-triMethyltridecyl)- 6-chroManol Acetate;Copherol 12250 |
| CAS: |
58-95-7 |
| MF: |
C31H52O3 |
| MW: |
472.74 |
| EINECS: |
200-405-4 |
| Product Categories: |
Antioxidant;Biochemistry;Pharmaceutical Raw Materials;Organics;Vitamins;EPHYNAL;Inhibitors |
| Mol File: |
58-95-7.mol |
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| D-alpha-Tocopheryl acetate Chemical Properties |
| Melting point |
~25 °C(lit.) |
| alpha |
3 º (c=2, in ethanol 25 ºC) |
| Boiling point |
224 °C0.3 mm Hg(lit.) |
| density |
0.953 g/mL at 25 °C(lit.) |
| refractive index |
n20/D 1.496(lit.) |
| Fp |
>230 °F |
| storage temp. |
2-8°C |
| solubility |
Practically insoluble in water, freely soluble in , in anhydrous ethanol and in fatty oils, soluble in ethanol (96 per cent). |
| form |
oil or semi-solid |
| color |
yellow |
| Water Solubility |
<0.1 g/100 mL at 17 ºC |
| Merck |
14,9495 |
| Stability: |
Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference |
58-95-7(CAS DataBase Reference) |
| NIST Chemistry Reference |
Vitamin e acetate(58-95-7) |
| EPA Substance Registry System |
D-.alpha.-Tocopheryl acetate (58-95-7) |
| Safety Statements |
24/25 |
| WGK Germany |
1 |
| RTECS |
GP8280000 |
| HS Code |
29362800 |
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| D-alpha-Tocopheryl acetate Usage And Synthesis |
| Description |
D-alpha-tocopheryl acetate is a natural form of vitamin E and it is stable in terms of shelf life. It is probably the best form for people actively trying to prevent heart disease. It is used in the dietary and clinical supplementations. |
| References |
[1] Jack Challem, User’s Guide to Nutritional Supplements, 2003
[2] M. K. Horwitt, Relative biological values of d-alpha-tocopheryl acetate and all-rac-alpha-tocopheryl acetate in man, The American Society for Clinical Nutrition, 1980, vol. 33, 1856-1860 |
| Chemical Properties |
off-white crystalline solid |
| Uses |
Used in prevention and treatment of vitamin E deficiencies. |
| General Description |
Odorless off-white crystals. Darkens at 401° F. |
| Air & Water Reactions |
D-alpha-Tocopheryl acetate may be sensitive to prolonged exposure to light and air. . Insoluble in water. |
| Reactivity Profile |
An ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. |
| Fire Hazard |
Flash point data for D-alpha-Tocopheryl acetate are not available. D-alpha-Tocopheryl acetate is probably combustible. |
| Contact allergens |
Tocopherol and tocopheryl acetate are used mainly as antioxidants. Tocopheryl acetate, an ester of tocopherol (vitamin E), can induce allergic contact dermatitis. |
| Safety Profile |
When heated to decomposition it emits acrid smoke and irritating fumes. |
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| D-alpha-Tocopheryl acetate Preparation Products And Raw materials |
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