| Sodium deoxycholate Basic information |
| Product Name: | Sodium deoxycholate |
| Synonyms: | OXIDE EXTRACT;SODIUM CHOLEATE;Deoxycholic acid, sodium salt, 99%, extra pure;Sodium Deoxycholate [for Electrophoresis];Deoxycholic acid sodium;Sodium deoxycholate ,98%;SodiuM 3,12-dihydroxycholanate;sodium 3-α,12-α-dihydroxy-5-β-cholan-24-oate |
| CAS: | 302-95-4 |
| MF: | C24H41NaO4 |
| MW: | 416.58 |
| EINECS: | 206-132-7 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Bile SaltsDetergents;Anionic;Detergents;Detergents A to Z; |
| Mol File: | 302-95-4.mol |
| Sodium deoxycholate Chemical Properties |
| Melting point | 357-365 °C |
| alpha | 44 º (c=2, H2O) |
| Fp | >110°C (own results) |
| storage temp. | Store at RT. |
| solubility | water: soluble1 gm in 10 ml, clear, colorless to very faintly yellow |
| form | Powder |
| color | Yellow-tan |
| Odor | Odorless |
| PH | 7.5-9.0 (20g/l, H2O, 20℃) |
| PH Range | 7 - 10 |
| optical activity | [α]20/D +44±2°, c = 2% in H2O |
| Water Solubility | 330 g/L (15 ºC) |
| BRN | 3581950 |
| CAS DataBase Reference | 302-95-4(CAS DataBase Reference) |
| EPA Substance Registry System | Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3.alpha.,5.beta.,12.alpha.)- (302-95-4) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22-37 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | FZ2250000 |
| F | 3-10 |
| TSCA | Yes |
| HS Code | 29181930 |
| Toxicity | LD50 orally in Rabbit: 1370 mg/kg |
| MSDS Information |
| Provider | Language |
|---|---|
| Sodium deoxycholate | English |
| ACROS | English |
| SigmaAldrich | English |
| Sodium deoxycholate Usage And Synthesis |
| Chemical Properties | Sodium deoxycholate is white to cream crystalline powder |
| Uses | Sodium deoxycholate is used as a component in cell lysis buffers. |
| Uses | Sodium deoxycholate is an ionic detergent for the solubilization of membrane-bound proteins. |
| Safety Profile | Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NasO. |
| Purification Methods | Recrystallise it from EtOH and dry it in an oven at 100o. The solution is freed from soluble components by repeated extraction with acid-washed charcoal. [Beilstein 10 IV 1608.] |