Sodium deoxycholate Basic information |
Product Name: | Sodium deoxycholate |
Synonyms: | OXIDE EXTRACT;SODIUM CHOLEATE;Deoxycholic acid, sodium salt, 99%, extra pure;Sodium Deoxycholate [for Electrophoresis];Deoxycholic acid sodium;Sodium deoxycholate ,98%;SodiuM 3,12-dihydroxycholanate;sodium 3-α,12-α-dihydroxy-5-β-cholan-24-oate |
CAS: | 302-95-4 |
MF: | C24H41NaO4 |
MW: | 416.58 |
EINECS: | 206-132-7 |
Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Bile SaltsDetergents;Anionic;Detergents;Detergents A to Z; |
Mol File: | 302-95-4.mol |
Sodium deoxycholate Chemical Properties |
Melting point | 357-365 °C |
alpha | 44 º (c=2, H2O) |
Fp | >110°C (own results) |
storage temp. | Store at RT. |
solubility | water: soluble1 gm in 10 ml, clear, colorless to very faintly yellow |
form | Powder |
color | Yellow-tan |
Odor | Odorless |
PH | 7.5-9.0 (20g/l, H2O, 20℃) |
PH Range | 7 - 10 |
optical activity | [α]20/D +44±2°, c = 2% in H2O |
Water Solubility | 330 g/L (15 ºC) |
BRN | 3581950 |
CAS DataBase Reference | 302-95-4(CAS DataBase Reference) |
EPA Substance Registry System | Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3.alpha.,5.beta.,12.alpha.)- (302-95-4) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 22-37 |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
RTECS | FZ2250000 |
F | 3-10 |
TSCA | Yes |
HS Code | 29181930 |
Toxicity | LD50 orally in Rabbit: 1370 mg/kg |
MSDS Information |
Provider | Language |
---|---|
Sodium deoxycholate | English |
ACROS | English |
SigmaAldrich | English |
Sodium deoxycholate Usage And Synthesis |
Chemical Properties | Sodium deoxycholate is white to cream crystalline powder |
Uses | Sodium deoxycholate is used as a component in cell lysis buffers. |
Uses | Sodium deoxycholate is an ionic detergent for the solubilization of membrane-bound proteins. |
Safety Profile | Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NasO. |
Purification Methods | Recrystallise it from EtOH and dry it in an oven at 100o. The solution is freed from soluble components by repeated extraction with acid-washed charcoal. [Beilstein 10 IV 1608.] |