Leader Biochemical Group 86--029-68895030 info@leader-biogroup.com
China Northwest Factory Manufacturer Hydroxocobalamin Cas 13422-51-0 For stock delivery

China Northwest Factory Manufacturer Hydroxocobalamin Cas 13422-51-0 For stock delivery

  • Purity
    99.9%
  • Use
    Health Care
  • Origin
    China
  • Package
    1KG/Tin 25KG/Drum*Carton
  • Manufacturer
    XI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
  • Place of Origin
    CHINA
  • Brand Name
    Leader
  • Certification
    ISO,GMP,SGS,HALA,KOSER,HACCP
  • Model Number
    LD
  • Minimum Order Quantity
    25KGS
  • Price
    Negotiate
  • Packaging Details
    25KG/Drum
  • Delivery Time
    2-3 working days
  • Payment Terms
    Western Union, MoneyGram, T/T, L/C
  • Supply Ability
    10MTS/Month

China Northwest Factory Manufacturer Hydroxocobalamin Cas 13422-51-0 For stock delivery

Hydroxocobalamin Basic information
Product Name: Hydroxocobalamin
Synonyms: alpha-(5,6-dimethylbenzimidazolyl)hydroxocobamide;alphacobione;alpharedisol;axion;axlon;ciplaminh;cobalex;vitaminb(sub12a)
CAS: 13422-51-0
MF: C62H90ClCoN13O15P
MW: 1382.82
EINECS: 236-533-2
Product Categories: pharmaceutical intermediate
Mol File: 13422-51-0.mol
Hydroxocobalamin Structure
 
Hydroxocobalamin Chemical Properties
Melting point >300 °C
storage temp. 2-8°C
solubility methanol: 10 mg/mL at 20 °C, clear, dark red
form neat
EPA Substance Registry System Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-.alpha.-D-ribofuranosyl-1H-benzimidazole-.kappa.N3) (13422-51-0)
 
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS GG3820000
F 3-8-10
Hazardous Substances Data 13422-51-0(Hazardous Substances Data)
Toxicity LD50 intravenous in mouse: > 50mg/kg
MSDS Information
Provider Language
Hydroxocobalamin English
SigmaAldrich English
 
Hydroxocobalamin Usage And Synthesis
Originator Alpha-Redisol,MSD,US,1962
Uses Vitamin (hematopoietic).
Definition A form of vitamin B 12.
Manufacturing Process A solution containing 26.3 mg of vitamin B12 in 15 ml of water was shaken with 78 mg of platinum oxide catalyst and hydrogen gas under substantially atmospheric pressure at 25°C for 20 hours. Hydrogen was absorbed. During the absorption of hydrogen the color of the solution changed from red to brown. The solution was separated from the catalyst and evaporated to dryness in vacuo. The residue was then dissolved in 1 ml of water and then diluted with about 6 ml of acetone.
After standing for several hours a small amount of precipitate (about 2 to 3 mg) was formed and was then separated from the solution. This solution was diluted with an additional 2 ml of acetone and again allowed to stand for several hours. During this time about 4 to 5 mg of noncrystalline precipitate formed. This solid was separated from the solution and an additional 2 ml of acetone was added to the solution. On standing, vitamin B12a began to crystallize in the form of red needles. After standing for 24 hours, the crystalline material was separated, yield 12 mg. By further dilution of the mother liquor with acetone additional crystalline precipitate formed (from US Patent 2,738,302).
Therapeutic Function Hematopoietic vitamin
 
Hydroxocobalamin Preparation Products And Raw materials
Raw materials Hydrogen-->Vitamin B12
Preparation Products HYDROXOCOBALAMIN HYDROCHLORIDE