China Northwest Factory Manufacturer Hydroxocobalamin Cas 13422-51-0 For stock delivery
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Purity99.9%
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UseHealth Care
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OriginChina
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Package1KG/Tin 25KG/Drum*Carton
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ManufacturerXI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
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Place of OriginCHINA
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Brand NameLeader
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CertificationISO,GMP,SGS,HALA,KOSER,HACCP
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Model NumberLD
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Minimum Order Quantity25KGS
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PriceNegotiate
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Packaging Details25KG/Drum
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Delivery Time2-3 working days
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Payment TermsWestern Union, MoneyGram, T/T, L/C
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Supply Ability10MTS/Month
China Northwest Factory Manufacturer Hydroxocobalamin Cas 13422-51-0 For stock delivery
| Hydroxocobalamin Basic information |
| Product Name: | Hydroxocobalamin |
| Synonyms: | alpha-(5,6-dimethylbenzimidazolyl)hydroxocobamide;alphacobione;alpharedisol;axion;axlon;ciplaminh;cobalex;vitaminb(sub12a) |
| CAS: | 13422-51-0 |
| MF: | C62H90ClCoN13O15P |
| MW: | 1382.82 |
| EINECS: | 236-533-2 |
| Product Categories: | pharmaceutical intermediate |
| Mol File: | 13422-51-0.mol |
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| Hydroxocobalamin Chemical Properties |
| Melting point | >300 °C |
| storage temp. | 2-8°C |
| solubility | methanol: 10 mg/mL at 20 °C, clear, dark red |
| form | neat |
| EPA Substance Registry System | Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-.alpha.-D-ribofuranosyl-1H-benzimidazole-.kappa.N3) (13422-51-0) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | GG3820000 |
| F | 3-8-10 |
| Hazardous Substances Data | 13422-51-0(Hazardous Substances Data) |
| Toxicity | LD50 intravenous in mouse: > 50mg/kg |
| MSDS Information |
| Provider | Language |
|---|---|
| Hydroxocobalamin | English |
| SigmaAldrich | English |
| Hydroxocobalamin Usage And Synthesis |
| Originator | Alpha-Redisol,MSD,US,1962 |
| Uses | Vitamin (hematopoietic). |
| Definition | A form of vitamin B 12. |
| Manufacturing Process | A solution containing 26.3 mg of vitamin B12 in 15 ml of water was shaken with 78 mg of platinum oxide catalyst and hydrogen gas under substantially atmospheric pressure at 25°C for 20 hours. Hydrogen was absorbed. During the absorption of hydrogen the color of the solution changed from red to brown. The solution was separated from the catalyst and evaporated to dryness in vacuo. The residue was then dissolved in 1 ml of water and then diluted with about 6 ml of . After standing for several hours a small amount of precipitate (about 2 to 3 mg) was formed and was then separated from the solution. This solution was diluted with an additional 2 ml of and again allowed to stand for several hours. During this time about 4 to 5 mg of noncrystalline precipitate formed. This solid was separated from the solution and an additional 2 ml of was added to the solution. On standing, vitamin B12a began to crystallize in the form of red needles. After standing for 24 hours, the crystalline material was separated, yield 12 mg. By further dilution of the mother liquor with additional crystalline precipitate formed (from US Patent 2,738,302). |
| Therapeutic Function | Hematopoietic vitamin |
| Hydroxocobalamin Preparation Products And Raw materials |
| Raw materials | Hydrogen-->Vitamin B12 |
| Preparation Products | HYDROXOCOBALAMIN HYDROCHLORIDE |
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