China Northwest Factory Manufacturer Indole-3-Carbinol Cas 700-06-1 For stock delivery
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Purity99.9%
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UseHealth Care
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OriginChina
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Package1KG/Tin 25KG/Drum*Carton
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ManufacturerXI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
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Place of OriginCHINA
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Brand NameLeader
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CertificationISO,GMP,SGS,HALA,KOSER,HACCP
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Model NumberLD
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Minimum Order Quantity25KGS
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PriceNegotiate
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Packaging Details25KG/Drum
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Delivery Time2-3 working days
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Payment TermsWestern Union, MoneyGram, T/T, L/C
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Supply Ability10MTS/Month
China Northwest Factory Manufacturer Indole-3-Carbinol Cas 700-06-1 For stock delivery
| Indole-3-carbinol Basic information |
| Product Name: | Indole-3-carbinol |
| Synonyms: | Indole-3-carbinol,99.5%;Indole-3-carbinol 98%;(1H-Indol-3-yl)-methano;Indol-3-yl-methanol;3-INDOLAMETHANOL;INDOLE-3-CARBINOL:3-INDOLE METHANOL;INDOLE-3-CARBINOL(RG);3-HYDROXYMETHYLINDOLE(INDOLE-3-CARBINOL) |
| CAS: | 700-06-1 |
| MF: | C9H9NO |
| MW: | 147.17 |
| EINECS: | 211-836-2 |
| Product Categories: | Heterocycle-Indole series;Antioxidant;Biochemistry;Simple Indoles;Nutritional Supplements;Aromatics;Indoles and derivatives;IndoleDerivative;Pyrroles & Indoles;Indole;Indoles;Heterocycles;Inhibitors;Pyrroles & Indoles;blocks;IndolesOxindoles;indole derivative;Halogenated Heterocycles ,Others;pharmaceutical raw material |
| Mol File: | 700-06-1.mol |
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| Indole-3-carbinol Chemical Properties |
| Melting point | 96-99 °C(lit.) |
| Boiling point | 267.28°C (rough estimate) |
| density | 1.1135 (rough estimate) |
| refractive index | 1.5670 (estimate) |
| storage temp. | 2-8°C |
| pka | 15.10±0.10(Predicted) |
| form | Crystalline Powder or Flakes |
| color | Off-white to yellow-orange |
| BRN | 121323 |
| Stability: | 2-80C |
| InChIKey | IVYPNXXAYMYVSP-UHFFFAOYSA-N |
| CAS DataBase Reference | 700-06-1(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| RTECS | NL9483000 |
| Hazard Note | Irritant |
| HS Code | 29339900 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| Indole-3-carbinol Usage And Synthesis |
| Chemical Properties | Off-White Powder |
| Uses | Inhibits cancinogenesis at the initiation stage. A metabolite of 3-methylindole |
| Uses | antineoplastic; inhibitor of Amyloid-beta deposition |
| Uses | nutritional supplement |
| Definition | ChEBI: An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity. |
| Synthesis Reference(s) | Canadian Journal of Chemistry, 31, p. 775, 1953 DOI: 10.1139/v53-106 The Journal of Organic Chemistry, 61, p. 1493, 1996 DOI: 10.1021/jo951219c |
| Anticancer Research | I3C is a bioactive compound majorly found in Brassica vegetables including broccoli,cauliflower, and collard greens. I3C and its derivative diindolylmethane (DIM)have been investigated for cancer prevention and treatment of breast, prostate, andovarian cancers. I3C partially modulates the tyrosine kinase/PI3K/Akt signalingpathway which leads to the prevention of lung adenocarcinoma which is induced byusing tobacco carcinogen in A/J mice. DIM transduces signaling via aryl hydrocarbon(Ah) receptor, NF-κB/Wnt/Akt/mTOR signaling pathways, cell cycle arrest,modulated cytochrome P450 enzymes, and altered angiogenetic and invasive,metastatic, and epigenetic behavior of cancer cells. Combination of DIM and I3Cinduces Nrf2-mediated phase II drug metabolizing genes (GSTm2, UGT1A1, andNQO1) and antioxidant genes (HO-1, SOD-1) (Weng et al. 2008; 2012). |
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