Leader Biochemical Group

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China Northwest Factory Manufacturer 2-Deoxy-D-ribose Cas 533-67-5 For stock delivery

China Northwest Factory Manufacturer 2-Deoxy-D-ribose Cas 533-67-5 For stock delivery

Brand Name: Leader
Model Number: LD
MOQ: 25KGS
Price: Negotiate
Payment Terms: Western Union, MoneyGram, T/T, L/C
Supply Ability: 10MTS/Month
Detail Information
Place of Origin:
CHINA
Certification:
ISO,GMP,SGS,HALA,KOSER,HACCP
Purity:
99.9%
Use:
Health Care
Origin:
China
Package:
1KG/Tin 25KG/Drum*Carton
Manufacturer:
XI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
Packaging Details:
25KG/Drum
Supply Ability:
10MTS/Month
Product Description
 
2-Deoxy-D-ribose Basic information
Product Name: 2-Deoxy-D-ribose
Synonyms: D-.alpha.-Ribodesose;Deoxyribose;D-Ribose, 2-deoxy-;2-deoxy-d-erythro-pentos;2-Deoxypentose;2-Desoxy ribosoe;D-(-)-2-DEOXYRIBOSE;D-2-DEOXYRIBOSE
CAS: 533-67-5
MF: C5H10O4
MW: 134.13
EINECS: 208-573-0
Product Categories: FINE Chemical & INTERMEDIATES;Pharmaceutical Raw Materials;13C & 2H Sugars;Riboses and 2'-Deoxyriboses;Biochemistry;Deoxysugars;Nucleosides, Nucleotides & Related Reagents;Ribose;Sugars;Dextrins,Sugar & Carbohydrates;aldehydes;Carbohydrates & Derivatives;nucleoside
Mol File: 533-67-5.mol
2-Deoxy-D-ribose Structure
 
2-Deoxy-D-ribose Chemical Properties
Melting point 89-90 °C(lit.)
alpha -57 º (c=1, H2O, 24hr)
Boiling point 167.23°C (rough estimate)
density 1.0590 (rough estimate)
refractive index -56 ° (C=1, H2O)
storage temp. 2-8°C
form Crystalline Powder
pka 12.61(at 25℃)
color White to slightly yellow
optical activity [α]22/D 59°, c = 1 in H2O
Water Solubility soluble
Sensitive Hygroscopic
Merck 14,2908
BRN 1721978
InChIKey ASJSAQIRZKANQN-CRCLSJGQSA-N
CAS DataBase Reference 533-67-5(CAS DataBase Reference)
NIST Chemistry Reference D-Erythro-pentose, 2-deoxy-(533-67-5)
EPA Substance Registry System D-erythro-Pentose, 2-deoxy- (533-67-5)
 
Safety Information
Hazard Codes Xn,Xi
Risk Statements 20/21/22-36/37/38
Safety Statements 24/25-37/39-36-26
WGK Germany 3
RTECS SB7230000
F 3-10
TSCA Yes
HS Code 29400000
MSDS Information
Provider Language
2-Deoxy-D-arabinose English
ACROS English
SigmaAldrich English
ALFA English
 
2-Deoxy-D-ribose Usage And Synthesis
Chemical Properties White powder
Uses 2-Deoxy-D-ribose induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.
Definition ChEBI: A deoxypentose that is D-ribose in which the hydroxy group at position C-2 is replaced by hydrogen.
Purification Methods Dissolve 2-deoxy--D-ribose in a little H2O, evaporate to a syrup (in a vacuum), and seed to crystallise. Triturate the crystals with a little EtOAc containing 5% MeOH, decant and dry in vacuum over P2O5. It is best purified via the anilide which separates from a mixture of the ribose (100-125g) in MeOH (100mL) and redistilled aniline (40mL) in a few minutes. After standing for 20hours at room temperature, it is cooled to 0o, filtered, washed with 50% aqueous MeOH and Et2O followed by recrystallisation from ethylene glycol monomethyl r. The anilide has m 172-173o, [ ] D 25 +46o (equilibrium in pyridine). The anilide (5g), benzaldehyde (5mL) and benzoic acid (0.5g) in H2O (150mL) are shaken mechanically for 2024hours. The aqueous phase is extracted with Et2O (3x), decolourised with a little charcoal and evaporated in a vacuum to a syrup. This is dried over P2O5 in high vacuum. The syrupy sugar weighs 3.1g and crystallises in a few days, but more rapidly on seeding. Triturate it with a little EtOAc containing 5% MeOH, decant and dry it over P2O5. At this stage it has m 78-82o, [ ] D 25 -57o (c 1, H2O final). This is a mixture of and anomers. Pure -anomer is obtained by recrystallisation from EtOAc The -anomer when recrystallised from EtOAc and isoPrOH has m 96-98o, [ ] D 25 -55o (c 0.5, H2O final). [Sowden Biochemical Preparations 5 75 1957.] The mutarotation is as follows: [] D 20.5 +96.3o(0minutes), -76o(33minutes), -56o (24hours) (c 5.8 MeOH). It is moderately hygroscopic and should be kept in a well stoppered bottle. It also crystallises from diethyl r. [Deriaz et al. J Chem Soc 1879 1949, Beilstein 1 IV 4181, Hauske & Rapoport J Org Chem 4 4 2472 1979.]