China Northwest Factory Manufacturer (Mecobalamin)/Methylcobalamin(Vitamin B12) Cas 13422-55-4 For stock delivery
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ColorRed
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UseHealth Care
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OriginChina
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Package1KG/Tin 25KG/Drum*Carton
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ManufacturerXI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
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Place of OriginCHINA
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Brand NameLeader
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CertificationISO,GMP,SGS,HALA,KOSER,HACCP
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Model NumberLD
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Minimum Order Quantity25KGS
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PriceUS10000-12000KG
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Packaging Details25KG/Drum
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Delivery Time2-3 working days
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Payment TermsWestern Union, MoneyGram, T/T, L/C
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Supply Ability10MTS/Month
China Northwest Factory Manufacturer (Mecobalamin)/Methylcobalamin(Vitamin B12) Cas 13422-55-4 For stock delivery
| Mecobalamin Basic information |
| Product Name: | Mecobalamin |
| Synonyms: | MECOBALAMIN;MECOBALAMINE;METHYLCOBALAMIN;cobalt-methylcobalamin;cobinamide,cobalt-methylderivative,hydroxide,dihydrogenphosphate(ester),;Methyl-5,6-dimethylbenzimidazolylcobalamin;Vitamin B12;Algobaz |
| CAS: | 13422-55-4 |
| MF: | C63H91CoN13O14P |
| MW: | 1344.38 |
| EINECS: | 236-535-3 |
| Product Categories: | API;Pharmaceutical intermediates;PHARMACEUTICALS;Nutritional Supplements;Intermediates & Fine Chemicals;Vitamin B12;Nutrition Research;Vitamins;Vitamin Ingredients |
| Mol File: | 13422-55-4.mol |
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| Mecobalamin Chemical Properties |
| Melting point | >190°C (dec.) |
| storage temp. | −20°C |
| pka | pK1:7.64(+1) (25°C) |
| Water Solubility | Partially soluble in cold water, hot water. |
| InChIKey | JEWJRMKHSMTXPP-WYVZQNDMSA-L |
| CAS DataBase Reference | 13422-55-4 |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25-36-26 |
| WGK Germany | 2 |
| RTECS | GG3745000 |
| HS Code | 29362600 |
| Toxicity | LD50 oral in rat: > 5gm/kg |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Mecobalamin Usage And Synthesis |
| Pharmacological action | Mecobalamin as vitamin B12 derivatives, should be called "methyl vitamin B12" according to the chemical structure of name, the functional groups of methylation can be involved in the biochemical process of methyl transfer activity, promoting to nucleic acid of nerve tissue, the metabolism of protein and fat, , can stimulate the synthesis of lecithin Schwann cells, repairing the damaged myelin, improving nerve conduction velocity; directly into nerve cells, and stimulating axon regeneration of damaged area; stimulating protein synthesis in nerve cells and enhanced synthetic metabolism of axons to prevent axonal degeneration; involved in nucleic acid synthesis, promoted hematopoietic function. The treatment is clinically used in diabetic neuropathy, long-term use of macrovascular complications of diabetes are the curative effect. Mecobalamin is used for peripheral nerve disorders treatment drug, compared with other vitamin B12 preparations, having good transfer on the nervous tissue, through the methyl transfer reaction, can promote nucleic acid, protein lipid metabolism, repairing the damaged nerve tissue. In homocysteine synthetic egg ammonia acid process, it plays a role of coenzyme, especially by deoxyuridine synthesis of thymidine, promoting DNA and RNA synthesis of participation. Also in the experiment of glial cells, the drugs can improve methionine synthase activity and promote the synthesis of myelin lipids lecithin. Improving the nerve tissue metabolism, can promot axis cable and protein synthesis, make the delivery rate of the skeletal protein close to normal, maintain axonal functions. Besides mecobalamin injections can inhibit nerve tissue of abnormal impulse conduction, promoting redl blood cells mature, split, improving anemia. Mecobalamin can be quickly restored due to lack of B12 and reduce the number of rat erythrocytes, hemoglobin, hematocrit value. Used for megaloblastic red blood cell anemia and peripheral nerve disorder due to the lack of vitamin B12. The above information is edited by the Chemicalbook Hanya. |
| Uses | 1.It is used for the treatment of nervous system diseases, relieving pain and numbness, speeded relieving pain, improving pain caused by cervical spondylosis, treatment of sudden deafness, etc. 2.Methylcobalamin is a kind of endogenous coenzyme B12, participating in the one carbon unit cycle, playing an important role in the synthesis of methionine homocysteine methyl transfer reaction process. |
| Chemical Properties | Dark Red Crystalline Powder |
| Uses | One of the biologically active forms of vitamin B12; differing only by the substitution of a methyl for the cyano group. Coenzyme required in the biosynthesis of methionine. Vitamin (hematopoietic). |
| Uses | ?Histamine receptor, Alzheimer research |
| Definition | A vitamin B 12 analog used as an intermediate in the synthesis of methane. It is responsible for the methylation of inorganic mercury by anaerobic bacteria in bottom sediments. Through the action of methylcobalamin in an anaerobic bacteria in bottom sediments of aquatic systems, arsenic(III) is methylated to methanearsonic acid then to cacodylic acid. |
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