Arbutin is a Hydroquinone glycoside compound. Its chemical name is 4-hydroxyphenyl-D-glucopyranoside. It exists in bear fruit, blueberry and other plants and is a new natural whitening active substance without irritation, allergy and strong compatibility. There are two structural and functional functional groups in the molecular structure of arbutin: one is glucose residues; The other is phenolic hydroxyl. α- The physical state of arbutin is white to light gray powder, which is easily soluble in water and ethanol. effect α- Arbutin has a good therapeutic effect on scars caused by UV burns, and has a good anti-inflammatory, repair and whitening effect. It can inhibit the production and deposition of melanin and remove color spots and freckles. Action mechanism α- The whitening mechanism of arbutin directly inhibits tyrosinase activity, thereby reducing melanin production, rather than inhibiting cell growth or tyrosinase gene expression to reduce melanin production. because α- Arbutin is a more efficient and safe whitening active substance, which has been adopted by many cosmetic companies at home and abroad α- Arbutin substitution β- Arbutin is used as whitening additive. The application of alphaChemicalbook arbutin is a chemical substance. alpha arbutin is similar to arbutin, which can inhibit the production and deposition of melanin and remove color spots and freckles. The results showed that - arbutin could inhibit the activity of tyrosinase at a relatively low concentration, and its inhibitory effect on tyrosinase was better than that of arbutin. Alpha arbutin can be used as a whitening agent in cosmetics. The samples obtained from the purification and identification reaction were first extracted by ethyl acetate, then by n-butanol, and then evaporated and collected by rotary evaporator. The obtained samples were centrifuged, and the supernatant was analyzed by HPLC α- HPLC chromatograms of arbutin standard were compared α- Whether arbutin has the same retention time, and preliminarily infer whether the sample contains α- Arbutin. The extracted and purified products were identified by LC-ESI-MS/MS positive ion mode. α- The relative molecular weight of bear fruit comparison products α- The relative molecular weight of arbutin standard can determine whether the product is α- Arbutin. Chemical property: white acicular crystal, soluble in methanol, ethanol, DMSO and other organic solvents, from bear fruit leaves and rock cabbage. purpose α- Arbutin can inhibit the activity of tyrosinase at a relatively low concentration, and its inhibitory effect on tyrosinase is better than arbutin
