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Tris(hydroxymethyl)aminomethane Basic information

description Chemical Properties Uses of Biology Uses

Product Name:	Tris(hydroxymethyl)aminomethane
Synonyms:	OmniPur TRIS -CAS 77-86-1 - Calbiochem;Tris Base, Molecular Biology Grade - CAS 77-86-1 - Calbiochem;Tris Base, ULTROL Grade - CAS 77-86-1 - Calbiochem;Tris Buffer, 1.0 M, pH 8.0, Molecular Biology Grade - CAS 77-86-1 - Calbiochem;Tris Buffer, 100 mM, pH 7.4, Molecular Biology Grade - CAS 77-86-1 - Calbiochem;Tris(Hydroxymethyl)aminomethane (Trometamol) high purity;1-[ethyl(hydroxymethyl)amino]ethane-1,2-diol;TRIS,Tromethamine, Trometamol
CAS:	77-86-1
MF:	C4H11NO3
MW:	121.14
EINECS:	201-064-4
Product Categories:	tris;Pharmaceutical intermediates;ACS Grade Buffers;Amino Alcohols;Biological Buffers;API;Biochemistry;Reagents for Electrophoresis;Buffer;Buffers A to Z;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;bc0001;77-86-1
Mol File:	77-86-1.mol

Tris(hydroxymethyl)aminomethane Chemical Properties

Melting point	167-172 °C(lit.)
Boiling point	219-220 °C10 mm Hg(lit.)
density	1,353 g/cm3
vapor pressure	0.0267 hPa (20 °C)
refractive index	1.4170 (estimate)
Fp	219-220°C/10mm
storage temp.	20-25°C
solubility	H2O: 4 M at 20 °C, clear, colorless
form	crystalline
color	white
PH	10.5-12.0(4 m in water, 25 °C)
pka	8.1(at 25℃)
PH Range	7 - 9
Water Solubility	550 g/L (25 ºC)
Sensitive	Hygroscopic
λmax	λ: 260 nm Amax: 0.10 λ: 280 nm Amax: 0.08
Merck	14,9772
BRN	741883
Stability:	Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
InChIKey	LENZDBCJOHFCAS-UHFFFAOYSA-N
LogP	-2.515 (est)
CAS DataBase Reference	77-86-1(CAS DataBase Reference)
NIST Chemistry Reference	1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1)
EPA Substance Registry System	Tris(hydroxymethyl)aminomethane (77-86-1)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39-24/25-23
WGK Germany	2
RTECS	TY2900000
F	3
TSCA	Yes
HazardClass	IRRITANT
HS Code	29221980
Hazardous Substances Data	77-86-1(Hazardous Substances Data)