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| Dithioerythritol Basic information |
| Product Name: |
Dithioerythritol |
| Synonyms: |
(S,R)-DITHIOERYTHRITOL;(r*,s*)-1,4-dimercapto-2,3-butanediol;1,4-dimercapto-,(r*,s*)-3-butanediol;1,4-dimercapto-,(theta,s)-3-butanediol;1,4-dithio-erythrito;DITHIOERYTHRITOL MOLECULAR BIOLOGY*REAGE NT;DITHIOERYTHRITOL, 99+%;DITHIOERYTHRITOL SIGMAULTRA |
| CAS: |
6892-68-8 |
| MF: |
C4H10O2S2 |
| MW: |
154.25 |
| EINECS: |
229-998-8 |
| Product Categories: |
Pharmaceutical Intermediates;Antioxidant;Biochemistry;Erythrose;O-Substituted Sugars;Sugar Alcohols;Sugars;proteinmod |
| Mol File: |
6892-68-8.mol |
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| Dithioerythritol Chemical Properties |
| Melting point |
82-84 °C(lit.) |
| Boiling point |
247.65°C (rough estimate) |
| density |
1.156 (estimate) |
| refractive index |
1.5200 (estimate) |
| storage temp. |
2-8°C |
| solubility |
H2O: 10 mg/mL, clear, colorless |
| pka |
pK1:9.5 (25°C) |
| form |
Powder |
| color |
White to pale yellow or beige |
| PH |
4.0-6.0 (25℃, 0.1M in H2O) |
| Water Solubility |
Soluble |
| λmax |
λ: 260 nm Amax: 0.400
λ: 280 nm Amax: 0.050 |
| Sensitive |
Air Sensitive |
| BRN |
1719756 |
| Stability: |
Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey |
VHJLVAABSRFDPM-ZXZARUISSA-N |
| CAS DataBase Reference |
6892-68-8(CAS DataBase Reference) |
| EPA Substance Registry System |
1,4-Dithioerythritol (6892-68-8) |
| |
| Dithioerythritol Usage And Synthesis |
| Chemical Properties |
White solid |
| Uses |
Reagent for the reduction of disulfide group. Prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis. Cleavage of disulfide bonds in proteins |
| Definition |
ChEBI: The meso-diastereomer of 1,4-dimercaptobutane-2,3-diol; a sulfur-containing sugar derived from the monosaccharide erythrose; and an epimer of dithiothreitol. |
| Purification Methods |
Crystallise DTE from r/hexane and store it in the dark at 0o. [Beilstein 1 III 2360.] |
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| Dithioerythritol Preparation Products And Raw materials |
