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| 3,5-Dimethylpyrazole Basic information |
| |
| 3,5-Dimethylpyrazole Chemical Properties |
| Melting point |
105-108 °C (lit.) |
| Boiling point |
218 °C (lit.) |
| density |
0,884 g/cm3 |
| refractive index |
1.4739 (estimate) |
| Fp |
210°C |
| storage temp. |
Sealed in dry,Room Temperature |
| solubility |
methanol: 0.1 g/mL, clear |
| pka |
15.12±0.10(Predicted) |
| form |
Crystalline Powder or Crystals |
| color |
White to almost white |
| PH |
6.7 (14g/l, H2O, 20℃) |
| Water Solubility |
Soluble in water, methanol 0.1 g/mL. |
| BRN |
106325 |
| InChIKey |
SDXAWLJRERMRKF-UHFFFAOYSA-N |
| CAS DataBase Reference |
67-51-6(CAS DataBase Reference) |
| NIST Chemistry Reference |
1H-Pyrazole, 3,5-dimethyl-(67-51-6) |
| EPA Substance Registry System |
3,5-Dimethylpyrazole (67-51-6) |
| Hazard Codes |
Xn,Xi |
| Risk Statements |
22-36/37/38 |
| Safety Statements |
26-36 |
| WGK Germany |
3 |
| RTECS |
UQ6477600 |
| Hazard Note |
Irritant |
| TSCA |
Yes |
| HazardClass |
IRRITANT |
| HS Code |
29331990 |
| |
| 3,5-Dimethylpyrazole Usage And Synthesis |
| Chemical Properties |
White crystal powder |
| Uses |
Common reagent for the preparation of pyrazolato ligated complexes.1,2 Also used to prepare N-1-substituted derivatives having antibacterial activity.3 |
| Uses |
3,5-Dimethylpyrazole is used as intermediate for the manufacture of organic dyestuffs and photochemicals. Product Data Sheet |
| Synthesis Reference(s) |
Journal of Heterocyclic Chemistry, 19, p. 373, 1982 DOI: 10.1002/jhet.5570190231
Organic Syntheses, Coll. Vol. 4, p. 351, 1963 |
| Purification Methods |
Crystallise it from cyclohexane or water. [Barszez et al. J Chem Soc, Dalton Trans 2025 1986, Beilstein 23/5 V 110.] |
| |
| 3,5-Dimethylpyrazole Preparation Products And Raw materials |
| Raw materials |
1H-Pyrazole, 3,5-dimethyl-1-[2-[(4-methylphenyl)sulfonyl]ethyl]--->1-(4-phenyl)-3,5-dimethyl-1H-Pyrazole-->ETHYL 3-AMINO-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXYLATE-->1-ALLYL-3 5-DIMETHYLPYRAZOLE 96-->1-CYANOACETYL-3,5-DIMETHYLPYRAZOLE-->4-Bromo-3,5-dimethylpyrazole-->Semicarbazide hydrochloride-->Hydrazine, hydrate (1:1)-->2,3-Pentanedione |
| Preparation Products |
4-Bromo-1,3,5-trimethyl-1H-pyrazole-->(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)M-->1,3,5-Trimethylpyrazole-->1,3,5-Trimethyl-1H-pyrazole-4-carboxaldehyde-->3,5-PYRAZOLEDICARBOXYLIC ACID-->1,3,5-TRIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID-->1H-Pyrazole-4-carbonyl chloride, 1,3,5-trimethyl- (9CI)-->DIETHYL 3,5-PYRAZOLEDICARBOXYLATE-->1,4-Dioxaspiro[4.5]decan-8-one-->3,5-DIMETHYLPYRAZOLE-1-METHANOL |
