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| 2-COUMARANONE Chemical Properties |
| Melting point |
49-51 °C(lit.) |
| Boiling point |
248-250 °C(lit.) |
| density |
1,22 g/cm3 |
| refractive index |
1.4800 (estimate) |
| Fp |
>230 °F |
| solubility |
H2O: soluble3.8g/L at 30°C |
| form |
Crystalline Powder or Crystals |
| color |
White to yellow-orange |
| BRN |
114689 |
| InChIKey |
ACZGCWSMSTYWDQ-UHFFFAOYSA-N |
| CAS DataBase Reference |
553-86-6(CAS DataBase Reference) |
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| 2-COUMARANONE Usage And Synthesis |
| Description |
2-Coumaranone (also named as Isophthalide, 3H-benzofuran-2-one) belongs to a class of organic compounds named as benzofuranones which exhibits mutagenic and carcinogenic activity. 2-Coumaranone has been used to study the effects of coumarins on 7,12-dimethyibenz(a)anthracene induced neoplasia of the rat mammary gland and as probe for detecting enzymes which hydrolyze 2-hydroxybenzofuran structures. |
| Reference |
Y. S. Priya, K. Ramachandra Rao, P. V. Chalapathi, M. Satyavani, A. Veeraiah, Vibrational and UV spectroscopic studies of 2-coumaranone by experimental and density functional theory calculations, Journal of Molecular Structure, 2017, vol. 1144, pp. 535-544 |
| Chemical Properties |
WHITE TO LIGHT YELLOW CRYSTALLINE POWDER |
| Synthesis Reference(s) |
The Journal of Organic Chemistry, 47, p. 2491, 1982 DOI: 10.1021/jo00133a055 |
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| 2-COUMARANONE Preparation Products And Raw materials |
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