| 6-Carboxyfluorescein Basic information |
| Product Name: |
6-Carboxyfluorescein |
| Synonyms: |
3-Oxo-3',6'-dihydroxy-1,3-dihydrospiro[isobenzofuran-1,9'-[9H]xanthene]-6-carboxylic acid;Carboxyfluorescein;3',6'-dihydroxy-1-keto-spiro[isobenzofuran-3,9'-xanthene]-5-carboxylic acid;3',6'-dihydroxy-1-oxo-spiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid;3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid;6-Carboxyfluorescein,6-FAM, FLUOS;6-Carboxyfluorescein Hydrate;6-FAM, 6-CF |
| CAS: |
3301-79-9 |
| MF: |
C21H12O7 |
| MW: |
376.32 |
| EINECS: |
636-503-2 |
| Product Categories: |
marker;Fluorescent Labels and Indicators;Electronic Chemicals;Fluorescent Labels & Indicators;Fluorescent;Xanthene |
| Mol File: |
3301-79-9.mol |
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| 6-Carboxyfluorescein Chemical Properties |
| Melting point |
>300 °C(lit.) |
| Boiling point |
736.4±60.0 °C(Predicted) |
| density |
1.73±0.1 g/cm3(Predicted) |
| storage temp. |
2-8°C |
| solubility |
DMSO: soluble |
| pka |
3.3, 4.6, 6.4, 7.0(at 25℃) |
| form |
Solid |
| color |
Yellow to orange |
| PH Range |
Weak green ' uorescence (6.0) to strong green ' uourescence (7.2) |
| λmax |
492nm |
| BRN |
54341 |
| Biological Applications |
Diagnosing bladder cancer; evaluating corneal endothelial barrier function; as a substrate for measuring protein kinase activity, methyltransferase activity, phospholipase activity, rhodanese activity,sulfotransferase activity;use in ophthalmology |
| Major Application |
Diagnosis of hematologic cancer, nongastric diseases, detection of genetically modified wheat, chromosomes, gene expression, nucleic acid, hepatitis A virus, avian influenza virus subtype H5 and H5N1, SARS virus, herpex simplex virus |
| CAS DataBase Reference |
3301-79-9(CAS DataBase Reference) |
| EPA Substance Registry System |
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 3',6'-dihydroxy-3-oxo- (3301-79-9) |
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| 6-Carboxyfluorescein Usage And Synthesis |
| Chemical Properties |
Orange Solid |
| Uses |
Derivative of fluorescein giving stable derivative upon conjugation with biopolymers. |
| Uses |
6-Carboxyfluorescein is a useful reagent for the preparation of hydrolytically stable fluorescent conjugates and is a useful starting material for the synthesis of other fluorescein-derives reagent |
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| 6-Carboxyfluorescein Preparation Products And Raw materials |
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