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The World Largest manufacturer Factory Sales Highest Quality P-Hydroxyacetophenone CAS 99-93-4

The World Largest manufacturer Factory Sales Highest Quality P-Hydroxyacetophenone CAS 99-93-4

  • Purity
    99.9%
  • Use
    Health Care
  • Origin
    China
  • Package
    1KG/Tin 25KG/Drum*Carton
  • Manufacturer
    XI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
  • Place of Origin
    CHINA
  • Brand Name
    info@leader-biogroup.com
  • Certification
    ISO,GMP,SGS,HALA,KOSER,HACCP
  • Model Number
    LD
  • Minimum Order Quantity
    25KGS
  • Price
    Negotiate Depend on order quantity
  • Packaging Details
    25KG/Drum
  • Delivery Time
    2-3 working days
  • Payment Terms
    Western Union, MoneyGram, T/T, L/C
  • Supply Ability
    10MTS/Month

The World Largest manufacturer Factory Sales Highest Quality P-Hydroxyacetophenone CAS 99-93-4

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4'-Hydroxyacetophenone Basic information
Product Name: 4'-Hydroxyacetophenone
Synonyms: 1-(4-hydroxyphenyl)-ethanon;4’-hydroxy-acetophenon;4-Hydroksyacetofenol;Acetophenone, p-hydroxy-;Ethanone, 1-(4-hydroxyphenyl)-;Hydroxyacetophenone, para;HYDROXYACETOPHENONE-4;HYDROXYBENZOPHENONE-4
CAS: 99-93-4
MF: C8H8O2
MW: 136.15
EINECS: 202-802-8
Product Categories: Pyridines;Pharmaceutical intermediates for Choleretic and Salbutamol;Aromatic Acetophenones & Derivatives (substituted);Aromatics;Miscellaneous Reagents;Eczema, medicine and other organic synthesis intermediates;Acetophenone Series;FINE Chemical & INTERMEDIATES;AcetophenoneCarbonyl Compounds;C7 to C8;Ketones;Organic Photoinitiators;Polymerization Initiators;Carbonyl Compounds
Mol File: 99-93-4.mol
4'-Hydroxyacetophenone Structure
 
4'-Hydroxyacetophenone Chemical Properties
Melting point 132-135 °C(lit.)
Boiling point 147-148 °C3 mm Hg(lit.)
density 1.109
FEMA 4330 | 4-HYDROXYACETOPHENONE
refractive index 1.5577 (estimate)
Fp 166 °C
storage temp. Refrigerator
solubility methanol: 0.1 g/mL, clear
form Crystalline Powder
pka 8.05(at 25℃)
Specific Gravity 1.109
color Almost white to beige
Water Solubility 10 g/L (22 ºC)
JECFA Number 2040
BRN 774355
InChIKey TXFPEBPIARQUIG-UHFFFAOYSA-N
CAS DataBase Reference 99-93-4(CAS DataBase Reference)
NIST Chemistry Reference Acetophenone, 4'-hydroxy-(99-93-4)
EPA Substance Registry System 4-Hydroxyacetophenone (99-93-4)
 
Safety Information
Hazard Codes Xn,Xi
Risk Statements 36/37/38-22
Safety Statements 26-36/37-37/39-24/25-22-36
WGK Germany 3
RTECS PC4959775
Hazard Note Irritant
TSCA Yes
HS Code 29145000
MSDS Information
Provider Language
1-(4-Hydroxyphenyl)ethanone English
SigmaAldrich English
ACROS English
ALFA English
 
4'-Hydroxyacetophenone Usage And Synthesis
Chemical Properties almost white to beige crystalline powder
Chemical Properties White to beige powder; sweet, hawthorn, balsam, mimosa aroma
Occurrence Reported found in cloudberry, coffee, cranberry, mango, sherry, and wort.
Preparation Preparation by Fries rearrangement of phenyl acetate with Lewis acids
aluminium chloride
in nitrobenzene at 20–25° or at 50–60°
in chlorobenzene between 45° and 65°, sealed tube and subjected to high power microwave irradiation for 2 min only (36%)
in nitroethane at 60° (44%)
in carbon disulfide at 45° (40%)
in petroleum r at 50° (20%)
but between 130° and 175° (40–60%)
aluminium chloride–sodium chloride mixture at 240–250° (10%)
boron trifluoride at 90° (56%)
scandium tris(trifluoromethanesulfonate), in nitromethane, at 50° (39%)
titanium tetrachloride at 90–100° (34%)
ferric chloride at 65° (25%)
zinc chloride at 125° (8%)
hydrofluoric acid, between 20° and 100° (94%)
polyphosphoric acid, between 20° and 100° (69%) (50–53%)(44%)
Nafion-XR 500, sulfonic acid type at 100°
ZSM-5, in sulfolane, at 180° (28%)
H-ZSM-5 at 400° or at 210° (6%)
H-Nu-2 at 170° (15%)
HY (Si/Al = 3) or fluorided alumina (Al2O3-F; 3 % wt. F), at 400°.
Definition ChEBI: A monohydroxyacetophenone carrying a hydroxy substituent at position 4'.
Aroma threshold values Floral type, medium strength odor; recommend smelling in a 10.00% solution or less.
Synthesis Reference(s) Tetrahedron Letters, 32, p. 5829, 1991 DOI: 10.1016/S0040-4039(00)93567-6
Purification Methods Crystallise it from diethyl r, aqueous EtOH or *benzene/pet r. [Beilstein 8 H 87, 8 IV 339.]