| (+)-Usniacin Basic information |
| Product Name: |
(+)-Usniacin |
| Synonyms: |
D-2,6-DIACETYL-7,9-DIHYDROXY-8,9BETA-DIMETHYL-1,3[2H,9BH]-DIBENZOFURANDIONE;D-USNIC ACID;TIMTEC-BB SBB006458;(+)-USNEIN;(+)-USNIACIN;(r)-usnicaci;3(2h,9bh)-dibenzofurandione,2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-(9b;6-diacetyl-1,7,9-trihydroxy-8,9b-dimethyl-d-3(9bh)-dibenzofuranon |
| CAS: |
7562-61-0 |
| MF: |
C18H16O7 |
| MW: |
344.32 |
| EINECS: |
231-456-0 |
| Product Categories: |
Inhibitors;Pharmaceutical Raw Materials;Plant Oils, Toxins, Phenolic Acids & Derivatives |
| Mol File: |
7562-61-0.mol |
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| (+)-Usniacin Chemical Properties |
| Melting point |
201-203 °C(lit.) |
| alpha |
488 º (c=0.4, CHCl3) |
| Boiling point |
399.43°C (rough estimate) |
| density |
1.2869 (rough estimate) |
| refractive index |
1.4790 (estimate) |
| storage temp. |
2-8°C |
| pka |
4.00±0.40(Predicted) |
| optical activity |
[α]25/D +488°, c = 0.7% in chloroform |
| Water Solubility |
Partly soluble in water. Soluble in , ethanol, chloroform and furfural. |
| Merck |
14,9893 |
| BRN |
96698 |
| CAS DataBase Reference |
7562-61-0(CAS DataBase Reference) |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| Safety Statements |
36 |
| WGK Germany |
3 |
| RTECS |
HP5295050 |
| F |
3-10 |
| HazardClass |
IRRITANT |
| HS Code |
29329990 |
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| (+)-Usniacin Usage And Synthesis |
| Uses |
Usnic acid is used as fragrance; preservative in deodorants; in anti ac ne formulations; antibiotic for topical application. |
| Contact allergens |
Usnic acid is a component of lichens, also used as a topical antibiotic. Allergic contact dermatitis from lichens occurs mainly occupationally in forestry and horticultural workers, and in lichen pickers. |
| Purification Methods |
This very weak acid is the natural form which is recrystallised from Me2CO, MeOH or *C6H6. At 25o it is soluble in H2O (<0.01%), Me2CO (0.77%), EtOAc (0.88%), MeOCH2CH2OH (0.22%) and furfural (7.32%). [Curd & Robertson J Chem Soc 894 1937, Barton & Brunn J Chem Soc 603 1953, resolution: Dean et al. J Chem Soc 1250 1953, synthesis: Barton et al. J Chem Soc 538 1956, Beilstein 18/5 V 586.] |
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| (+)-Usniacin Preparation Products And Raw materials |
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