| Daidzein Basic information |
| Product Name: | Daidzein |
| Synonyms: | 4’,7-dihydroxy-isoflavon;DAIDZEIN;Daidsein;4,7-Dihydroxyisoflavone(Daidzein);DAIDZEIN, (AMERICAN HERBAL PHARMACOPOEIA);DAIDZEIN, 98% SYNTHETIC;DAIDZEIN, STANDARD FROM SOYBEAN 99+%(HPLC);DAIDZEIN:4',7-DIHYDROXY ISOFLAVONE |
| CAS: | 486-66-8 |
| MF: | C15H10O4 |
| MW: | 254.24 |
| EINECS: | 207-635-4 |
| Product Categories: | pharmacetical;Biochemistry;Iso-Flavones;Flavonoids;The group of Daidzin;Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;inhibitor;natural product;API;Tyrosine Kinase Inhibitors;Intracellular receptor;Indazoles |
| Mol File: | 486-66-8.mol |
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| Daidzein Chemical Properties |
| Melting point | 315-323°C (dec.) |
| Boiling point | 317.45°C (rough estimate) |
| density | 1.1629 (rough estimate) |
| refractive index | 1.4300 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO: 10 mg/mL |
| pka | 7.01±0.20(Predicted) |
| form | Powder |
| color | White to off-white |
| Water Solubility | insoluble |
| Merck | 14,2801 |
| BRN | 231523 |
| CAS DataBase Reference | 486-66-8(CAS DataBase Reference) |
| EPA Substance Registry System | 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)- (486-66-8) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/38 |
| Safety Statements | 24-26-37/39 |
| WGK Germany | 3 |
| RTECS | DJ3100040 |
| HazardClass | IRRITANT |
| HS Code | 29329990 |
| MSDS Information |
| Provider | Language |
|---|---|
| 4',7-Dihydroxyisoflavone | English |
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| Daidzein Usage And Synthesis |
| Chemical Properties | Off-White Crystalline Solid |
| Uses | Inactive analog of Genistein (Cat. #G350000). Blocks the G1 phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity1. Daidzein has also been shown to inhibit the action of GABA on recombinant GABAA receptors2. uv max:250 nm (log e 4.44) |
| Uses | Daidzein belongs to the group of isoflavones. Daidzein and other isoflavone compounds, such as genistein, are present in a number of plants and herbs. Soy isoflavones are a group of compounds found in and isolated from the soybean. Besides functioning as |
| Uses | phytoestrogen |
| Definition | ChEBI: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy group at position 4'. |
| Biological Activity | Analog of the phytoestrogen genistein (5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one ). Blocks G 1 phase cell cycle progression and is an agonist at estrogen receptors. |
| Daidzein Preparation Products And Raw materials |
| Raw materials | Ethanol-->Hydrochloric acid-->Diethyl r |
| Preparation Products | 6,7,4'-Trihydroxyisoflavone |