| Quinine hydrochloride dihydrate Basic information |
| Product Name: | Quinine hydrochloride dihydrate |
| Synonyms: | (R)(6--4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol monohydrochloride dihydrate;Cinchonan-9-ol, 6--, monohydrochloride, dihydrate, (8.alpha.,9R)-;QUININEHYDROCHLORIDE,DIHYDRATE,CRYSTAL;Quinine Monohy;Quinine HCl Dihydrate;(8α,9R)-6'--cinchonan-9-ol,hydrochloride, hydrate (1:1:2);(8α, 9R)-6′-cinchonan-9-ol monohydrochloride dihydrate;Quinine monohydrochloride dihydrate Vetec(TM) reagent grade, 88% |
| CAS: | 6119-47-7 |
| MF: | C20H27ClN2O3 |
| MW: | 378.9 |
| EINECS: | 612-097-2 |
| Product Categories: | API;Alkaloids;Biochemistry;for Resolution of Acids;Optical Resolution;Quinoline Alkaloids;Synthetic Organic Chemistry;AlkaloidAntibiotics;Antibiotics A to;Antibiotics N-SAntibiotics;Spectrum of Activity;Alphabetical Listings;Flavors and Fragrances;Q-Z;chiral;Antiparasitic / Antiprotozoal / AnthelminthicVoltage-gated Ion Channels;Biochemicals Found in Plants;Monovalent Ion Channels;Nutrition Research;Potassium Channel Modulators;Other APIs;Inhibitors |
| Mol File: | 6119-47-7.mol |
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| Quinine hydrochloride dihydrate Chemical Properties |
| Melting point | 115-116 °C (dec.)(lit.) |
| alpha | [α]D20 -245～-255° (c=2, dil. HCl) (After Drying) |
| FEMA | 2976 | QUININE HYDROCHLORIDE |
| refractive index | -250 ° (C=2, EtOH) |
| Fp | 122 °C |
| storage temp. | Store at -20°C |
| solubility | H2O: soluble0.25/5g/mL, clear, colorless |
| form | Crystalline Powder or Silky Needles |
| color | White to off-white |
| PH | 6.0 (10g/l, H2O, 20℃) |
| optical activity | [α]22/D 235°, c = 2 in 0.1 M HCl |
| Water Solubility | Sparingly soluble in water.(0.26 g/L) (25°C), |
| Sensitive | Light Sensitive |
| Merck | 14,8061 |
| BRN | 6112655 |
| InChIKey | MPQKYZPYCSTMEI-HPVDNOPASA-N |
| CAS DataBase Reference | 6119-47-7(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-42/43-36/37/38-20/21/22 |
| Safety Statements | 22-36/37-45-36/37/39-26-36 |
| RIDADR | 1544 |
| WGK Germany | 3 |
| RTECS | VA7700000 |
| F | 8 |
| Hazard Note | Irritant |
| HS Code | 29392000 |
| Toxicity | LD50 orally in Rabbit: 620 mg/kg |
| MSDS Information |
| Provider | Language |
|---|---|
| ACROS | English |
| SigmaAldrich | English |
| Quinine hydrochloride dihydrate Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde |
| Uses | Antiprotozoal (malaria). |