| Ecdysone Basic information |
| Product Name: |
Ecdysone |
| Synonyms: |
2,3,14,22,25-pentahydroxy-,(2-beta,3-beta,5-beta,22r)-cholest-7-en-6-on;2-beta,3-beta,14,22,25-pentahydroxy-,(20s,22r)-5-beta-cholest-7-en-6-on;ECDYSONE;ECDYSONE, ALPHA-;ALPHA-ECDYSON;ALPHA-ECDYSONE;ALPHA-ECDYSTERONE;7,(5-ALPHA)-CHOLESTEN-2-BETA, 3-BETA, 14-ALPHA, 22R, 25-PENTOL-6-ONE |
| CAS: |
3604-87-3 |
| MF: |
C27H44O6 |
| MW: |
464.63 |
| EINECS: |
222-760-4 |
| Product Categories: |
Natural Plant Extract; |
| Mol File: |
3604-87-3.mol |
 |
| |
| Ecdysone Chemical Properties |
| Melting point |
242°C |
| alpha |
20578 +62° |
| Boiling point |
488.1°C (rough estimate) |
| density |
1.0493 (rough estimate) |
| refractive index |
1.4482 (estimate) |
| storage temp. |
2-8°C |
| pka |
14.07±0.70(Predicted) |
| Merck |
13,3525 |
| BRN |
2422986 |
| CAS DataBase Reference |
3604-87-3(CAS DataBase Reference) |
| Safety Statements |
22-24/25 |
| WGK Germany |
3 |
| RTECS |
FZ8170000 |
| F |
10 |
| |
| Ecdysone Usage And Synthesis |
| Metabolic pathway |
When white mice are administered 3H-ecdyson, (2b,3b,14a,22(R),25-pentahydroxy-5b-cholest-7-ene-6- one) by injection intraperitoneally, ecdysone is metabolized via hydroxylation at C14, followed by reduction of ring B into the 6a-hydroxy derivative and epimerization at C3. |
| Purification Methods |
Recrystallise -ecdyson from tetrahydrofuran/pet r and from H2O as a hydrate. It has been purified by chromatogaphy on Al2O3 and elution with EtOAc/MeOH. It has max at 242nm ( 12,400). Its acetate has m 214-216o from EtOAc/pet r, and the 2,4-dinitrophenylhydrazone has m 170-175o(dec) from EtOAc. [Karlson & Hoffmeister Justus Liebigs Ann Chem 662 1 1963, Karlson Pure Appl Chem 14 75 1967, Beilstein 8 IV 3613.] |
| |
Ecdysone Preparation Products And Raw materials
|
|
