Leader Biochemical Group 86--029-68895030 info@leader-biogroup.com
China Largest Factory Manufacturer Lcariin CAS 489-32-7 For stock delivery

China Largest Factory Manufacturer Lcariin CAS 489-32-7 For stock delivery

  • Purity
    99.9%
  • Use
    Health Care
  • Origin
    China
  • Package
    1KG/Tin 25KG/Drum*Carton
  • Manufacturer
    XI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
  • Place of Origin
    CHINA
  • Brand Name
    Leader
  • Certification
    ISO,GMP,SGS,HALA,KOSER,HACCP
  • Model Number
    LD
  • Minimum Order Quantity
    25KGS
  • Price
    Negotiate Depend on order quantity
  • Packaging Details
    25KG/Drum
  • Delivery Time
    2-3 working days
  • Payment Terms
    Western Union, MoneyGram, T/T, L/C
  • Supply Ability
    10MTS/Month

China Largest Factory Manufacturer Lcariin CAS 489-32-7 For stock delivery

Icariin Basic information
Applications Description References
Product Name: Icariin
Synonyms: Horny goat weed extract;ICARIINE;ICARRIN;epimedium extract;Epimedium herb Ext;Epimedium P.E;Icariin, froM EpiMediuM davidii Franch;Icariin Min 90%
CAS: 489-32-7
MF: C33H40O15
MW: 676.66
EINECS: 610-440-0
Product Categories: Plant extracts;chemical reagent;Functional Products;plant extract;Nutritional Ingredients;pharmaceutical intermediate;Natural Plant Extract;The group of Epimedii;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Standardized plant extract;Inhibitors;API;Flavones
Mol File: 489-32-7.mol
Icariin Structure
 
Icariin Chemical Properties
Melting point 223-225 ºC
alpha D15 -87.09° (in pyridine)
Boiling point 948.5±65.0 °C(Predicted)
density 1.55
RTECS DJ2980500
storage temp. room temp
solubility DMSO: soluble50mg/mL, clear, colorless to dark yellow
form Powder
pka 5.90±0.40(Predicted)
color light yellow to yellow
λmax 350nm(MeOH)(lit.)
Merck 14,3617
InChIKey TZJALUIVHRYQQB-XLRXWWTNSA-N
 
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29389090
MSDS Information
 
 
Icariin Usage And Synthesis
Applications

Icariin inhibits the ROS-dependent JNK and p38 pathways.

Description Icariin is one of the major flavonoids of the herb Epimedium, which has long been used in Tranditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Research has shown that icariin should be an effective component for the bone-strengthening activity of the herb Epimedium, and one of the possible mechanisms for this activity is to stimulate the proliferation and enhance the osteogenic differentiation of marrow stromal cells. Icariin is reported to prevent and treat dysfunction related diseases and improve the use of vasoconstriction. Icariin is used to prepare angiotensin converting enzyme inhibitor medicines, which can be used to treat hypertension-complicated coronary diseases.
References [1] K. M. Chen, B. F. Ge, H. P. Ma, X. Y. Liu, M. H. Bai, Y, Wang (2005) Icariin, a flavonoid from the herb Epimedium enhances the osteogenic differentiation of rat primary bone marrow stromal cells, 60, 939-942
[2] Patent CN 1199647C “Application of icariin in preparation of medicine for preventing and treating dysfunction”
[3] Patent CN 104739851 A “New application of icariin, or icariin derivatives or icariin salt”
Chemical Properties

Light yellow to yellow solid
China Largest Factory Manufacturer Lcariin CAS 489-32-7 For stock delivery 1

Uses hepatoprotective