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China Largest Factory Manufacturer Deglycyrrhizinated licorice/DGL/liquorice CAS 1405-86-3 For stock delivery

China Largest Factory Manufacturer Deglycyrrhizinated licorice/DGL/liquorice CAS 1405-86-3 For stock delivery

  • Purity
    99.9%
  • Use
    Health Care
  • Origin
    China
  • Package
    1KG/Tin 25KG/Drum*Carton
  • Manufacturer
    XI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
  • Place of Origin
    CHINA
  • Brand Name
    Leader
  • Certification
    ISO,GMP,SGS,HALA,KOSER,HACCP
  • Model Number
    LD
  • Minimum Order Quantity
    25KGS
  • Price
    Negotiate Depend on order quantity
  • Packaging Details
    25KG/Drum
  • Delivery Time
    2-3 working days
  • Payment Terms
    Western Union, MoneyGram, T/T, L/C
  • Supply Ability
    10MTS/Month

China Largest Factory Manufacturer Deglycyrrhizinated licorice/DGL/liquorice CAS 1405-86-3 For stock delivery

Glycyrrhizic acid Basic information
Description References
Product Name: Glycyrrhizic acid
Synonyms: Glycyrrhizic acid 1405-86-3;Glycyrrhizic acid,from licorice;GLYCYRRHIZIN;GLYCYRRHIZINATE;GLYCYRRHYCIC ACID;GLYCYRRHIZIC ACID;GLYCYRRHETINIC ACID GLYCOSIDE;3-o-(2-o-beta-d-glucopyranuronosyl-alpha-d-glucopyranuronosyl)-18beta-g lycyrrhetinic acid
CAS: 1405-86-3
MF: C42H62O16
MW: 822.94
EINECS: 215-785-7
Product Categories: Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Tri-Terpenoids;Biochemistry;Disaccharides;Glycosides;Sugars;The group of Liquorice
Mol File: 1405-86-3.mol
Glycyrrhizic acid Structure
 
Glycyrrhizic acid Chemical Properties
Melting point 220°C (rough estimate)
alpha D17 +46.2° (c = 1.5 in alc)
Boiling point 681.01°C (rough estimate)
density 1.1442 (rough estimate)
refractive index 61 ° (C=1.5, EtOH)
pka 2.76±0.70(Predicted)
Merck 14,4505
InChIKey BXFBITNYMHAJGT-KYXJNIQISA-N
CAS DataBase Reference 1405-86-3
EPA Substance Registry System Glycyrrhizin (1405-86-3)
 
Safety Information
Safety Statements 22-24/25
WGK Germany 3
RTECS MD2025000
HS Code 29389090
Hazardous Substances Data 1405-86-3(Hazardous Substances Data)
 
Glycyrrhizic acid Usage And Synthesis
Description Glycyrrhizic acid is a kind of anti-inflammatory triterpene glycoside extracted from the licorice root. Inside the body, it can be metabolized to glycyrrhetinic acid which inhibits the 11-beta-hydroxy dehydrogenase and some other enzymes related to the cortico metabolism. Glycyrrhizic acid has various pharmacological effects including suppressing hepatic apoptosis and necrosis, anti-inflammatory and immune regulatory actions, antiviral effects, antineoplastic and anticancer effects. It is the active ingredient of licorice root which is commonly used in the treatment of acute and chronic liver injury, viral hepatitis, hepatic steatosis, liver fibrosis, hepatoma, viral myocarditis and other diseases such as psoriasis or prostate cancer. Glycyrrhizic acid is also widely used as a sweetening and flavoring agent in food.
References https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052927/
https://pubchem.ncbi.nlm.nih.gov/compound/Glycyrrhizic_acid#section=Top
Chemical Properties White to off-white powder
Chemical Properties Glycyrrhizin, also known as glycyrrhizic acid, is a glycoside isolated from the roots of licorice, Glycyrrhiza glabra L. For improved water solubility, an ammoniated salt is commonly used. This can be in the form of either ammonium glycyrrhizinate or monoammonium glycyrrhizinate.
Uses Glycyrrhizin is a flavorant and foaming agent derived from the separation of flavonoids found in the whole licorice extract from the licorice root glycyrrhiza glabra. It is 50–100 times as sweet as sugar, is soluble in water, and has a licorice taste. It has good heat stability but prolonged heating can result in some degradation. It is stable within ph 4–9; below ph 4 there could be precipitation. It has foaming and emulsifying properties in water, being used in cocktail mixes and soft drinks. It is used as a flavorant in bacon and imitation whipped products. It is synergistic with sugar, the sweetness being amplified to 100 times that of cane sugar alone. It is used as a sweetener in sugar-free chewing gum and low-fat sugar-free frozen desserts. It is also termed ammoniated glycyrrhizin. Monoammonium glycyrrhizinate is obtained by additional refinement.
Uses glycyrrhizic acid is a hydrolyzed glycyrrhizin. It is credited with antiinflammatory and anti-allergenic properties. Studies comparing glycyrrhizin with hydrocortisone found glycyrrhizin to be somewhat milder but longer lasting in effectiveness. once the application of hydrocortisone is suspended, the symptoms return. This does not appear to be the case with glycyrrhizin. It does not have side effects and is chemically stable so it can be safely used on a continuing basis.
Uses 11beta-hydroxy dehydrogenase inhibitor, antiinflammatory, expectorant, antihaemorrhagic, anti-HIV
Uses Glycyrrhizic acid is a triterpene saponin used in the traditional Chinese medicinal preparation for its anti-inflammatory , antiulcerous and antiallergic effects.
Definition ChEBI: A triterpenoid saponin that is the glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid.
Safety Profile Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by ingestion: somnolence and changes in the metabolism of phosphorus, When heated to decomposition it emits acrid smoke and irritating fumes.