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China Largest Factory Manufacturer L-Proline CAS 147-85-3 For stock delivery

China Largest Factory Manufacturer L-Proline CAS 147-85-3 For stock delivery

  • Purity
    99.9%
  • Use
    Health Care
  • Origin
    China
  • Package
    1KG/Tin 25KG/Drum*Carton
  • Manufacturer
    XI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
  • Place of Origin
    CHINA
  • Brand Name
    Leader
  • Certification
    ISO,GMP,SGS,HALA,KOSER,HACCP
  • Model Number
    LD
  • Minimum Order Quantity
    25KGS
  • Price
    Negotiate Depend on order quantity
  • Packaging Details
    25KG/Drum
  • Delivery Time
    2-3 working days
  • Payment Terms
    Western Union, MoneyGram, T/T, L/C
  • Supply Ability
    10MTS/Month

China Largest Factory Manufacturer L-Proline CAS 147-85-3 For stock delivery

L-Proline Basic information
Product Name: L-Proline
Synonyms: L-Proline ,L-2-Pyrrolidinecarboxylic acid;L-PROLINE, NATURAL;L-PROLINE, SYNTHETIC;L-(-)-PROLINE ((S)-(-)-PROLINE);L-PROLINE (13C5, 99%);L-PROLINE (13C5, 99%;L-PROLINE (D7, 97-98%);L(-)-Proline 0
CAS: 147-85-3
MF: C5H9NO2
MW: 115.13
EINECS: 205-702-2
Product Categories: amino;Amino Acids;alpha-Amino Acids;Biochemistry;Nutritional Supplements;L-Amino Acids;Food & Feed ADDITIVES;Amino Acid Derivatives;Proline [Pro, P];Amino Acids;Amino Acids and Derivatives
Mol File: 147-85-3.mol
L-Proline Structure
 
L-Proline Chemical Properties
Melting point 228 °C (dec.)(lit.)
alpha -85.5 º (c=4, H2O)
Boiling point 215.41°C (rough estimate)
density 1.35
FEMA 3319 | L-PROLINE
refractive index -85 ° (C=4, H2O)
storage temp. Store at RT.
solubility H2O: 50 mg/mL
pka 1.95, 10.64(at 25℃)
form powder
color White
PH 6.0-7.0 (25℃, 1M in H2O)
optical activity [α]20/D 85.0±1.0°, c = 5% in H2O
Water Solubility soluble
λmax λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05
Sensitive Hygroscopic
JECFA Number 1425
Merck 14,7780
BRN 80810
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey ONIBWKKTOPOVIA-UHFFFAOYSA-N
CAS DataBase Reference 147-85-3(CAS DataBase Reference)
NIST Chemistry Reference Proline(147-85-3)
EPA Substance Registry System L-Proline (147-85-3)
 
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-22
Safety Statements 24/25-36/37/39-26
WGK Germany 3
RTECS TW3584000
F 3-10
TSCA Yes
HS Code 29339990
Hazardous Substances Data 147-85-3(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: > 5110 mg/kg
MSDS Information
Provider Language
2-Pyrrolidinecarboxylic acid English
ACROS English
SigmaAldrich English
ALFA English
 
L-Proline Usage And Synthesis
Chemical Properties White crystalline powder
Chemical Properties L-Proline, an amino acid, is odorless or has a slight, characteristic odor with a slightly sweet taste.
Occurrence Reported found as a component in many proteins; also widely occurring as the free acid in natural products. A major constituent of collagen, the main fibrous protein found in bone, cartilage and other connective tissue.
Uses amino acid, nutrient
Uses L-Proline is an amino acid and precursor (with vitamin C) for collagen, the building block of the structure of tendons, ligaments, arteries, veins and muscles. It is important in wound healing.
Preparation From α-piperidone; from cyclopentantone; from l-glutamic acid.
Purification Methods A likely impurity is hydroxyproline. Purify L-proline via its picrate which is crystallised twice from water, then decomposed with 40% H2SO4. The picric acid is extracted with diethyl r, the H2SO4 in solution is precipitated with Ba(OH)2, and the filtrate is evaporated. The residue is crystallised from hot absolute EtOH [Mellan & Hoover J Am Chem Soc 73 3879 1951] or EtOH/Et2O. Its solubility in H2O is >100%. It sublimes at 182-187o/0.3mm with 99.4% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. It is hygroscopic and is stored in a desiccator. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2178-2199 1961, Beilstein 22 III/IV 8, 22/1 V 31.]