D-(-)-Salicin Basic information |
Product Name: | D-(-)-Salicin |
Synonyms: | D-(-)-SALICIN;D-SALICIN;2-(HYDROXYMETHYL)PHENYL-BETA-D-GLUCOPYRANOSIDE;2-(HYDROXYMETHYL)PHENYL-BETA-D-GLUCOPYYRANOSIDE;2-(HYDROXYMETHYL)PHENYL-BETA-D-GLUCOSIDE;2-(Hydroxymethyl)phenyl hexopyranoside;SALICYLALDEHYDE-B-D-GLUCOSIDE;SALICYLALCOHOL BETA-D-GLUCOSIDE |
CAS: | 138-52-3 |
MF: | C13H18O7 |
MW: | 286.28 |
EINECS: | 205-331-6 |
Product Categories: | chemical reagent;pharmaceutical intermediate;Plant extract;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Sugars, Carbohydrates & Glucosides;Biochemistry;Glucose;Glycosides;Sugars;Natural Plant Extract;Herbs & Natural Remedies;HISMANAL;carbohydrate;Inhibitors |
Mol File: | 138-52-3.mol |
D-(-)-Salicin Chemical Properties |
Melting point | 196-202 °C |
alpha | -61.5 º (c=5, water) |
Boiling point | 388.65°C (rough estimate) |
density | 1.4340 |
refractive index | -62 ° (C=3, H2O) |
storage temp. | Store at RT. |
solubility | 36g/l |
pka | 12.80±0.70(Predicted) |
form | Fine Crystalline Powder |
color | White |
Water Solubility | 36 g/L (15 ºC), 250 g/L (60 ºC) |
Merck | 14,8324 |
BRN | 89593 |
Stability: | Stability Stable, but light sensitive. Incompatible with strong oxidizing agents. |
InChIKey | NGFMICBWJRZIBI-MICYEWLZSA-N |
CAS DataBase Reference | 138-52-3(CAS DataBase Reference) |
NIST Chemistry Reference | Salicin(138-52-3) |
EPA Substance Registry System | .beta.-D-Glucopyranoside, 2-(hydroxymethyl)phenyl (138-52-3) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 43 |
Safety Statements | 36/37-37-24/25-36 |
WGK Germany | 3 |
RTECS | LZ5901700 |
F | 3-10 |
TSCA | Yes |
HS Code | 29389090 |
MSDS Information |
Provider | Language |
---|---|
2-(Hydroxymethyl)phenyl-beta-D-glucopyranoside | English |
ACROS | English |
SigmaAldrich | English |
ALFA | English |
D-(-)-Salicin Usage And Synthesis |
Description | D(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities, it can inhibit the LPS-induced inflammation in RAW264.7 cells and mouse models. |
Chemical Properties | white crystals or powder |
Uses | analgesic, antipyretic |
Uses | H1 antihistamine (nonsedating) |
Uses | Standard substrate in evaluating enzyme Preparations contg b-glucosidase: Weidenhagen, Z. Ver. Zucker-Ind. 79, 591 (1929). |
Definition | ChEBI: An aryl beta-D-glucoside that is the beta-D-glucoside of the phenolic hydroxy group of salicyl alcohol. |
Purification Methods | Crystallise D(-)-salicin from EtOAc, EtOH or water and sublime it at 190-195o/12mm. [Armour et al. J Chem Soc 412 1961, IR: Pearl & Darling J Org Chem 24 731 1959, Beilstein 17 III/IV 2986, 17/7 V 113.] |
D-(-)-Salicin Preparation Products And Raw materials |