Leader Biochemical Group

products details

Created with Pixso. Home Created with Pixso. Products Created with Pixso.
Cosmetics Ingredients
Created with Pixso.

China Northwest Factory Manufacturer Betulinic Acid Cas 472-15-1 For stock delivery

China Northwest Factory Manufacturer Betulinic Acid Cas 472-15-1 For stock delivery

Brand Name: Leader
Model Number: LD
MOQ: 25KGS
Price: Negotiate
Payment Terms: Western Union, MoneyGram, T/T, L/C
Supply Ability: 10MTS/Month
Detail Information
Place of Origin:
CHINA
Certification:
ISO,GMP,SGS,HALA,KOSER,HACCP
Purity:
99.9%
Use:
Health Care
Origin:
China
Package:
1KG/Tin 25KG/Drum*Carton
Manufacturer:
XI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
Packaging Details:
25KG/Drum
Supply Ability:
10MTS/Month
Product Description
Betulinic acid Basic information
Product Name: Betulinic acid
Synonyms: Betulinic acid technical grade, 90%;3BETA-HYDROXY-20(29)-LUPENE-28-OIC ACID;3BETA-HYDROXY-20(29)-LUPAENE-28-OIC ACID;3B-HYDROXY-20(29)-LUPENE-28-OIC ACID;(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentaMethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylic acid;Birch bark extract/β-Amyrin/betulinic acid;3-B-HYDROXY-LUPA-20(30)-ENE 28-OIC ACID;BETULINIC ACID
CAS: 472-15-1
MF: C30H48O3
MW: 456.71
EINECS: 207-448-8
Product Categories: Tri-Terpenoids;sy;Pentacyclic Triterpenes;chemical reagent;Inhibitors;Triterpenoids;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Antineoplastic;natural product
Mol File: 472-15-1.mol
Betulinic acid Structure
 
Betulinic acid Chemical Properties
Melting point 295-298 °C (dec.)(lit.)
alpha D25 +7.5° (c = 0.37 in pyridine)
Boiling point 550.0±33.0 °C(Predicted)
density 1.065±0.06 g/cm3(Predicted)
refractive index 7.8 ° (C=0.9, Pyridine)
storage temp. Store at +4°C
form neat
pka 4.61±0.70(Predicted)
optical activity [α]20/D +7.8°, c = 0.9 in pyridine
Merck 14,1190
InChIKey QGJZLNKBHJESQX-FZFNOLFKSA-N
CAS DataBase Reference 472-15-1(CAS DataBase Reference)
 
Safety Information
Hazard Codes Xi
Safety Statements 24/25
WGK Germany 3
HS Code 29181985
MSDS Information
Provider Language
SigmaAldrich English
 
Betulinic acid Usage And Synthesis
Chemical Properties colorless Needles
Uses antineoplastic
Uses Betulinic Acid is a natural pentacyclic triterpenoid. Betulinic Acid displays anti-inflammatory and anti-HIV activity. Betulinic Acid selectively induces apoptosis in tumor cells by directly activati ng the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity
Definition ChEBI: A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium cla iflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties.
Biological Activity Natural triterpenoid that displays anti-HIV and antitumor activity. Induces the production of reactive oxygen species (ROS) and activates NF- κ B. Exhibits TRG5 agonist activity (EC 50 = 1.04 μ M).
Anticancer Research This compound is a pentacyclic triterpene obtained from Betula and Zizyphus species,which shows selective cytotoxicity against human melanoma cells (Shoeb2006). It generates reactive oxygen species, activates MAPK cascade, inhibitstopoisomerase I, inhibits angiogenesis, modulates pro-growth transcriptionalactivators, modulates the activity of aminopeptidase-N, and thereby inducesapoptosis in cancer cells (Desai et al. 2008; Fulda 2008).
 
Betulinic acid Preparation Products And Raw materials
Raw materials betulonic aldehyde
Preparation Products Betulin