Ecdysone Basic information |
Product Name: | Ecdysone |
Synonyms: | 2,3,14,22,25-pentahydroxy-,(2-beta,3-beta,5-beta,22r)-cholest-7-en-6-on;2-beta,3-beta,14,22,25-pentahydroxy-,(20s,22r)-5-beta-cholest-7-en-6-on;ECDYSONE;ECDYSONE, ALPHA-;ALPHA-ECDYSON;ALPHA-ECDYSONE;ALPHA-ECDYSTERONE;7,(5-ALPHA)-CHOLESTEN-2-BETA, 3-BETA, 14-ALPHA, 22R, 25-PENTOL-6-ONE |
CAS: | 3604-87-3 |
MF: | C27H44O6 |
MW: | 464.63 |
EINECS: | 222-760-4 |
Product Categories: | Natural Plant Extract; |
Mol File: | 3604-87-3.mol |
Ecdysone Chemical Properties |
Melting point | 242°C |
alpha | 20578 +62° |
Boiling point | 488.1°C (rough estimate) |
density | 1.0493 (rough estimate) |
refractive index | 1.4482 (estimate) |
storage temp. | 2-8°C |
pka | 14.07±0.70(Predicted) |
Merck | 13,3525 |
BRN | 2422986 |
CAS DataBase Reference | 3604-87-3(CAS DataBase Reference) |
MSDS Information |
Provider | Language |
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SigmaAldrich | English |
Ecdysone Usage And Synthesis |
Metabolic pathway | When white mice are administered 3H-ecdyson, (2b,3b,14a,22(R),25-pentahydroxy-5b-cholest-7-ene-6- one) by injection intraperitoneally, ecdysone is metabolized via hydroxylation at C14, followed by reduction of ring B into the 6a-hydroxy derivative and epimerization at C3. |
Purification Methods | Recrystallise -ecdyson from tetrahydrofuran/pet r and from H2O as a hydrate. It has been purified by chromatogaphy on Al2O3 and elution with EtOAc/MeOH. It has max at 242nm ( 12,400). Its acetate has m 214-216o from EtOAc/pet r, and the 2,4-dinitrophenylhydrazone has m 170-175o(dec) from EtOAc. [Karlson & Hoffmeister Justus Liebigs Ann Chem 662 1 1963, Karlson Pure Appl Chem 14 75 1967, Beilstein 8 IV 3613.] |