| beta-Sitosterol Basic information |
| Product Name: | beta-Sitosterol |
| Synonyms: | B-SITOSTEROL;5-STIGMASTEN-3BETA-OL;22,23-DIHYDROSTIMASTEROL;22,23-DIHYDROSTIGMASTEROL;24-ALPHA-ETHYLCHOLESTEROL;24BETA-ETHYLCHOLESTEROL;5-CHOLESTEN-24-BETA-ETHYL-3-BETA-OL;(3)-BETA-SITOSTEROL(2) |
| CAS: | 83-46-5 |
| MF: | C29H50O |
| MW: | 414.72 |
| EINECS: | 201-480-6 |
| Product Categories: | Inhibitors;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;Miscellaneous Natural Products;Biochemistry;Hydroxy;;Natural Plant Extract;Intermediates & Fine Chemicals;Pharmaceuticals;standardized herbal extract |
| Mol File: | 83-46-5.mol |
| beta-Sitosterol Chemical Properties |
| Melting point | 136-140 °C(lit.) |
| alpha | -28 º (c=2, CHCl3) |
| Boiling point | 473.52°C (rough estimate) |
| density | 0.9540 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| storage temp. | −20°C |
| solubility | chloroform: 20 mg/mL, clear, colorless |
| pka | 15.03±0.70(Predicted) |
| form | White solid |
| Water Solubility | INSOLUBLE |
| Merck | 14,8556 |
| BRN | 1916165 |
| InChIKey | KZJWDPNRJALLNS-VJSFXXLFSA-N |
| CAS DataBase Reference | 83-46-5(CAS DataBase Reference) |
| NIST Chemistry Reference | «beta»-Sitosterol(83-46-5) |
| EPA Substance Registry System | .beta.-Sitosterol (83-46-5) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-38-40-48/20/22-36/37/38-67-36/38-20-63 |
| Safety Statements | 22-24/25-36-26-36/37 |
| RIDADR | UN 1888 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | WJ2600000 |
| F | 10 |
| HS Code | 29061990 |
| MSDS Information |
| Provider | Language |
|---|---|
| ACROS | English |
| SigmaAldrich | English |
| beta-Sitosterol Usage And Synthesis |
| Chemical Properties | White powder |
| Uses | A common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma. |
| Uses | antiinflammatory, immunomodulator |
| Definition | ChEBI: A phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3. |
| Definition | A with long aliphatic side chains (8–10 carbons) and at least one hydroxyl group. They are lipidsoluble and often occur in membranes. Examples are cholesterol and ergosterol. |
| Definition | sterol: Any of a group of basedalcohols having a hydrocarbonside-chain of 8–10 carbon atoms.Sterols exist either as free sterols oras esters of fatty acids. Animal sterols(zoosterols) include cholesterol andlanosterol. The major plant sterol(phytosterol) is beta-sitosterol, whilefungal sterols (mycosterols) includeergosterol. |
| Purification Methods | Crystallise -sitosterol from EtOH, MeOH, Me2CO, Me2CO/EtOH or Me2CO/MeOH. It has also been purified by zone melting. The acetate crystallises from MeOH or EtOH as plates with m 127128o and [] D 20 -41o (c 2, CHCl3). The benzoate crystallises from EtOH as needles with m 146-147o and [] D 20 –13.8o (c 2, CHCl3). [Fujimoto & Jacobson J Org Chem 29 3377, 3381 1964, Shoppee J Chem Soc 10431948, Heilbron et al. J Chem Soc 344, 347 1941, Beilstein 6 III 2696.] |