Leader Biochemical Group

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China Northwest Factory Manufacturer Fusidic Acid Cas 6990-06-3 For stock delivery

China Northwest Factory Manufacturer Fusidic Acid Cas 6990-06-3 For stock delivery

Brand Name: Leader
Model Number: LD
MOQ: 25KGS
Price: US1500-2000KG
Payment Terms: Western Union, MoneyGram, T/T, L/C
Supply Ability: 10MTS/Month
Detail Information
Place of Origin:
CHINA
Certification:
ISO,GMP,SGS,HALA,KOSER,HACCP
Color:
White
Use:
Cosmetics
Origin:
China
Package:
1KG/Tin 25KG/Drum*Carton
Manufacturer:
XI'AN LEADER BIOCHEMICAL ENGINEERING CO.,LTD
Packaging Details:
25KG/Drum
Supply Ability:
10MTS/Month
Product Description
Fusidine Usage And Synthesis
Mode of action Fusidic acid forms a stable complex with an elongation factor (EF-G) involved in translocation and with guanosine triphosphate (GTP), which provides energy for the translocation process. One round of translocation occurs, with hydrolysis of GTP, but the fusidic acid–EF-G–GDP complex cannot dissociate from the ribosome, thereby blocking further chain elongation and leaving peptidyl-tRNA in the P site.
Although protein synthesis in Gram-negative bacilli–and, indeed, mammalian cells–is susceptible to fusidic acid, the antibiotic penetrates poorly into these cells and the spectrum of action is virtually restricted to Gram-positive bacteria, notably staphylococci.
Chemical Properties White Solid
Uses Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
Uses antibacterial
Definition ChEBI: A antibiotic that is isolated from the fermentation broth of Fusidium coccineum.
Brand name Fucidine (Bristol-Myers Squibb).
Hazard Moderately toxic inhibitor of translocation during protein synthesis.